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- A short DNA segment that occurs only once in the human genome and whose exact location and order of bases are known. Because each is unique, STSs are helpful for chromosome placement of mapping and sequencing data from many different laboratories. STSs serve as landmarks on the physical map of the human genome. See also chromosome, genome, mapping
National Human Genome Research Institute - Cite This Source - This Definition
- Short (200 to 500 base pairs) DNA sequence that has a single occurrence in the human genome and whose location and base sequence are known. Detectable by polymerase chain reaction, STSs are useful for localizing and orienting the mapping and sequence data reported from many different laboratories and serve as landmarks on the developing physical map of the human genome. Expressed sequence tags (ESTs) are STSs derived from cDNAs.
Human Genome Project - Cite This Source - This Definition
- Directed sequencing, Expressed sequence tag (EST), GC-rich area, Gene prediction, homeobox, microsatellite, repetitive DNA, scaffold, Tandem repeat sequences, Transposable element