Promoter
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- A region of DNA extending 150-300 bp upstream from the transcription start site that contains binding sites for RNA polymerase and a number of proteins that regulate the rate of transcription of the adjacent gene. (See Constitutive promoter.)
Susan Allender-Hagedorn and Charles Hagedorn - Cite This Source - This Definition - 1. A short DNA sequence, usually upstream of (5' to) the relevant coding sequence, to which RNA polymerase binds before initiating transcription. This binding aligns the RNA polymerase so that transcription will initiate at a specific site. The nucleotide sequence of the promoter determines the nature of the enzyme that attaches to it and the rate of RNA synthesis. 2. A chemical substance that enhances the transformation of benign cells into cancerous cells. See: constitutive promoter.
UN Food and Agriculture Organization - Cite This Source - This Definition - A regulatory element that specifies the start site of transcription.
USDA CSREES - Cite This Source - This Definition - aflatoxins, CAAT box, repression, Repressor, sigma factor
- The part of a gene that contains the information to turn the gene on or off. The process of transcription is initiated at the promoter. See also gene, protein
National Human Genome Research Institute - Cite This Source - This Definition - A DNA site to which RNA polymerase will bind and initiate transcription.
Human Genome Project - Cite This Source - This Definition - chimeraplasty, Gene expression, Intron, Splice site, Transcription, transcription factor, Translation, western blot