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A type of monoclonal antibody used in cancer detection or therapy. Monoclonal antibodies are laboratory-produced substances that can locate and bind to cancer cells.
- Browse Related Terms: 3F8, A33, alemtuzumab, AMG 162, apolizumab, BB-10901, Bexxar regimen, bispecific antibody, bispecific monoclonal antibody, Campath-1H, cBR96-doxorubicin immunoconjugate, CC-49, cCLB8, CNTO 328, denosumab, edrecolomab, epitope, galiximab, gemtuzumab, gemtuzumab ozogamicin, GM2-KLH vaccine, hA20, HCD20, hu14.18-interleukin-2 fusion protein, Hu3S193, HuAFP31, HuHMFG1, HuLuc63, HuMax-CD20, IMMU-106, immunoscintigraphy, lexatumumab, M200, MDX-060, MORAb-009, muJ591, muromonab-CD3, Mylotarg, ofatumumab, oregovomab, OvaRex, pertuzumab, pM-81, Prost 30, radioimmunodiagnostics, RAV12, Rituxan, rituximab, SGN-15, synthetic retinoid, systemic radiation therapy, tositumomab and iodine I 131 tositumomab, volociximab, yttrium
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An enzyme that is used as a biomarker to detect damage to the kidneys, and that may be used to help diagnose certain kidney disorders. It is found at high levels in the urine when there are kidney problems. Also called alanine aminopeptidase.
- Browse Related Terms: AAP, alanine aminopeptidase, Blood Urea Nitrogen, BUN, calcitriol, creatinine, dialysis, hypernephroma, kidney function test, nephrotoxic, renal cell cancer, renal function test, renal glomerulus, renal tubular acidosis, urea nitrogen
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(a-ba-REL-iks) A drug used to reduce the amount of testosterone made in patients with advanced symptomatic prostate cancer for which no other treatment options are available. It belongs to the family of drugs called gonadotropin-releasing hormone (GnRH) antagonists. Also called Plenaxis.
- Browse Related Terms: abarelix, Actos, azacitidine, Eloxatin, Mylosar, oxaliplatin, pioglitazone, Plenaxis, Trelstar, triptorelin, Vidaza
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A staging system for prostate cancer that uses ABCD. "A" and "B" refer to cancer that is confined to the prostate. "C" refers to cancer that has grown out of the prostate but has not spread to lymph nodes or other places in the body. "D" refers to cancer that has spread to lymph nodes or to other places in the body. Also called Jewett staging system and Whitmore-Jewett staging system.
- Browse Related Terms: ABCD rating, developmental stage, Dukes classification, early-stage cancer, embryo, embryonic, Jewett staging system, stage A prostate cancer, stage B prostate cancer, stage C prostate cancer, stage D prostate cancer, stage II prostate cancer, Whitmore-Jewett staging system
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(AB-doh-men) The area of the body that contains the pancreas, stomach, intestines, liver, gallbladder, and other organs.
- Browse Related Terms: abdomen, abdominal, ampulla of Vater, digestive system, gastrointestinal tract, hepatic portal vein, Pancreas, pancreatic, pancreatic duct, portal vein, sialyl Tn-KLH, unresectable gallbladder cancer
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Having to do with the abdomen, which is the part of the body between the chest and the hips that contains the pancreas, stomach, intestines, liver, gallbladder, and other organs.
- Browse Related Terms: abdomen, abdominal, ampulla of Vater, digestive system, gastrointestinal tract, hepatic portal vein, Pancreas, pancreatic, pancreatic duct, portal vein, sialyl Tn-KLH, unresectable gallbladder cancer
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(ab-DAH-mih-nul EX-ray) An x-ray of the organs inside the abdomen. An x-ray is a type of radiation that can pass through the body and onto film, making pictures of areas inside the body. X-rays may be used to help diagnose disease.
- Browse Related Terms: abdominal x-ray, bone marrow aspiration, cell proliferation, chest X-ray, diagnostic mammogram, dosimetry, Gamma-Ray, Mammogram, neuroradiologist, proliferative index, PTC, Radiologist, radiology, radon, respirator, screening mammogram, thoracodynia, x-ray
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Surgery to remove the anus, the rectum, and part of the sigmoid colon through an incision made in the abdomen. The end of the intestine is attached to an opening in the surface of the abdomen and body waste is collected in a disposable bag outside of the body. This opening is called a colostomy. Lymph nodes that contain cancer may also be removed during this operation.
- Browse Related Terms: abdominoperineal resection, amputation, anterior pelvic exenteration, axillary dissection, axillary lymph node dissection, cervicectomy, continent reservoir, decortication, exenteration, lung, neck dissection, pelvic exenteration, posterior pelvic exenteration, rectal reconstruction, resectable, resection, segmental resection, sleeve resection
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(uh-BAYR-unt KRIPT FOH-sy) Clusters of abnormal tube-like glands in the lining of the colon and rectum. Aberrant crypt foci form before colorectal polyps and are one of the earliest changes that can be seen in the colon that may lead to cancer. Also called ACF.
- Browse Related Terms: aberrant crypt foci, ACF, Appendix, cecum, colitis, colon, colon crypt, colon polyp, diverticulosis, gland of Lieberkuhn, intracolonic, large intestine, sigmoid colon
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A drug used to treat breast cancer that has spread or that has come back within 6 months after chemotherapy. It is also being studied in the treatment of newly diagnosed breast cancer and other types of cancer. ABI-007 is a type of mitotic inhibitor. Also called Abraxane, nanoparticle paclitaxel, paclitaxel albumin-stabilized nanoparticle formulation, and protein-bound paclitaxel.
- Browse Related Terms: ABI-007, Abraxane, nanoparticle paclitaxel, paclitaxel, paclitaxel albumin-stabilized nanoparticle formulation, protein-bound paclitaxel, Taxol
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(a-BLAY-shun) In medicine, the removal or destruction of a body part or tissue or its function. Ablation may be performed by surgery, hormones, drugs, radiofrequency, heat, or other methods.
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Not normal. An abnormal lesion or growth may be cancerous, premalignant (likely to become cancer), or benign.
- Browse Related Terms: abnormal, cervical intraepithelial neoplasia, cervical intraepithelial neoplasia grade 2/3, cervical squamous intraepithelial neoplasia 1, cervical squamous intraepithelial neoplasia 2, CIN, CIN 1, CIN 2, CIN 2/3, erythema, HSIL, low-grade squamous intraepithelial lesion, LSIL, lymphoepithelioma, neuroepithelial, SIL, squamous intraepithelial lesion
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(ab-nohr-MAL-uh-tee): A growth or area of tissue that is not normal. An abnormality may be cancer or likely to become cancer.
- Browse Related Terms: abnormality, antiangiogenesis therapy, breast cancer, colon cancer, dysphagia, mesothelioma, peripheral neuropathy, prostate cancer, quartile, TNM, toxicity
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(uh-BRAX-ayn) A drug used to treat breast cancer that has spread or that has come back within 6 months after chemotherapy. It is also being studied in the treatment of newly diagnosed breast cancer and other types of cancer. Abraxane is a type of mitotic inhibitor. Also called ABI-007, nanoparticle paclitaxel, paclitaxel albumin-stabilized nanoparticle formulation, and protein-bound paclitaxel.
- Browse Related Terms: ABI-007, Abraxane, nanoparticle paclitaxel, paclitaxel, paclitaxel albumin-stabilized nanoparticle formulation, protein-bound paclitaxel, Taxol
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An enclosed collection of pus in tissues, organs, or confined spaces in the body. An abscess is a sign of infection and is usually swollen and inflamed.
- Browse Related Terms: abscess, areola, CerviPrep, desmoid tumor, ethmoid sinus, frontal sinus, gingiva, gums, intrapelvic, pelvic, pelvis, sacrum, sphenoid sinus
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(ub-SORP-shun) The process of taking nutrients from the digestive system into the blood so they can be used in the body.
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A substance being studied in the treatment of lymphomas and other types of cancer. It blocks some of the enzymes that keep cancer cells from dying. It is a type of Bcl-2 family inhibitor.
- Browse Related Terms: 852A, ABT-263, BI 2536, ispinesib, MK0752, Nipent, obatoclax mesylate, pentostatin, PT-100, RTA 744, SB-715992, SNX-5422, SNX-5422 mesylate, talabostat, talabostat mesylate, topoisomerase II inhibitor RTA 744, topoisomerase inhibitor
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A substance being studied in the treatment of cancer. It is a type of angiogenesis inhibitor.
- Browse Related Terms: ABT-510, acridine carboxamide, chloroquinoxaline sulfonamide, CQS, DACA, ecteinascidin 743, edotecarin, epipodophyllotoxin, ET-743, FR901228, J-107088, romidepsin, soblidotin, trabectedin, TZT-1027
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A substance that is being studied in the treatment of cancer. It belongs to the family of drugs called sulfonamides.
- Browse Related Terms: ABT-751, acitretin, alanosine, annamycin, atamestane, BAY 56-3722, BAY 59-8862, BBR 2778, BBR 3464, beta alethine, BL22 immunotoxin, budesonide, CC-8490, cevimeline, darbepoetin alfa, E7070, E7389, eflornithine, EP-2101, EPO906, epratuzumab, ERA-923, everolimus, gabapentin, GTI-2040, halofuginone hydrobromide, ibandronate, lometrexol, lutetium texaphyrin, MLN2704, MLN591DM1, modafinil, motexafin lutetium, nimustine, OGX-011, perifosine, perillyl alcohol, phenobarbital, phenylbutyrate, PI-88, pirfenidone, pixantrone, PV701, pyrazoloacridine, R-flurbiprofen, ravuconazole, rebeccamycin, retinyl palmitate, rhizoxin, RPR 109881A, SDX-102, SGN-00101, SJG-136, staurosporine, suramin, T900607, talotrexin, taurolidine, triamcinolone, trimetrexate glucuronate, ursodiol, velafermin, vitamin E, XRP9881, zileuton
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A substance being studied in the treatment of some types of cancer. It blocks enzymes that repair DNA damage caused by cancer treatments such as radiation and drugs. ABT-888 is a type of poly(ADP-ribose) polymerase inhibitor.
- Browse Related Terms: ABT-888, AZD2281, batracylin, BSI-201, declopramide, Dimericine, OXi-104, PR-104, sedoxantrone trihydrochloride, SNP, T4N5 liposomal lotion, thymidine