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A substance being studied in the treatment of melanoma and many other types of cancer. D-1MT blocks the breakdown of the amino acid tryptophan, which is needed for T cells (a type of immune system cell) to kill tumor cells. Giving D-1MT to patients who have received chemotherapy for cancer may help kill more tumor cells. It is a type of enzyme inhibitor and immunosuppressant. Also called 1-methyl-d-tryptophan.
- Browse Related Terms: 1-methyl-d-tryptophan, Actinex, D-1MT, EM-1421, masoprocol, NDGA, nordihydroguaiaretic acid, Se-methyl-seleno-L-cysteine, tetra-O-methyl NDGA, tetra-O-methyl nordihydroguaiaretic acid
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A synthetic luteinizing hormone-releasing hormone (LH-RH) antagonist that suppresses LH and sex steroid levels.
- Browse Related Terms: androgen ablation, androgen deprivation, androgen suppression, antiandrogen, antiandrogen therapy, Avodart, cyproterone acetate, D-20761, deslorelin, dutasteride, endothelin receptor antagonist, finasteride, GG745, ketoconazole, LH-RH agonist, luteinizing hormone-releasing hormone agonist, nilutamide, nonsteroidal aromatase inhibitor, rapid hormone cycling
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A procedure to remove tissue from the cervical canal or the inner lining of the uterus. The cervix is dilated (made larger) and a curette (spoon-shaped instrument) is inserted into the uterus to remove tissue. Also called dilatation and curettage and dilation and curettage.
- Browse Related Terms: curettage, D&C, dilatation and curettage, dilation and curettage, suction aspiration, suction evacuation, vacuum aspiration
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(...SY-kloh-SER-een) A drug used to treat tuberculosis. It is also being studied in the treatment of pain and nerve problems (numbness, tingling) caused by chemotherapy and in the treatment of low back pain, autism, certain anxiety disorders, and schizophrenia. D-cycloserine is a type of antibiotic. Also called Seromycin .
- Browse Related Terms: Adderall, amitriptyline, amitriptyline hydrochloride, D-cycloserine, dextroamphetamine-amphetamine, flecainide, Keppra, levetiracetam, Lyrica, pregabalin, Seromycin, valproic acid
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(dah-hwong) The root of this plant has been used in some cultures to treat certain medical problems. It may have anti-inflammatory and anticancer effects. The scientific name is Rheum palmatum or Rheum officinale . Also called Chinese rhubarb, Indian rhubarb, rhubarb, and Turkish rhubarb.
- Browse Related Terms: Chinese rhubarb, da-huang, Indian rhubarb, rhubarb, Turkish rhubarb
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A substance being studied in the treatment of cancer. It is a type of topoisomerase inhibitor. Also called acridine carboxamide.
- Browse Related Terms: ABT-510, acridine carboxamide, chloroquinoxaline sulfonamide, CQS, DACA, ecteinascidin 743, edotecarin, epipodophyllotoxin, ET-743, FR901228, J-107088, romidepsin, soblidotin, trabectedin, TZT-1027
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An anticancer drug that is a type of alkylating agent.
- Browse Related Terms: anthraquinone, arsenic trioxide, buthionine sulfoximine, chemoembolization, cilengitide, crisnatol mesylate, cyclosporine, dacarbazine, di-dgA-RFB4, EMD 121974, estramustine, fazarabine, flavopiridol, flutamide, gossypol, hyperuricemia, ILX23-7553, leflunomide, liarozole, LU 79553, LU-103793, mitotane, multidrug resistance, multidrug resistance inhibition, N-acetyldinaline, platinum, remission induction therapy, ribonucleotide reductase inhibitor, stereotactic injection, SU101, TG4010, tiazofurin, tinnitus, tocladesine, Trisenox, troxacitabine
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A monoclonal antibody that is being studied in the treatment of adult T-cell leukemia and in the treatment of cytopenia (low blood cell count). Also called daclizumab.
- Browse Related Terms: Avastin, bevacizumab, coactivated T cell, conditioning regimen, dacliximab, daclizumab, efalizumab, infliximab, ipilimumab, MDX-010, MEDI-507, Raptiva, siplizumab, targeted therapy, ticilimumab, tositumomab
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A monoclonal antibody that is being studied in the treatment of adult T-cell leukemia and in the treatment of cytopenia (low blood cell count). Also called dacliximab.
- Browse Related Terms: Avastin, bevacizumab, coactivated T cell, conditioning regimen, dacliximab, daclizumab, efalizumab, infliximab, ipilimumab, MDX-010, MEDI-507, Raptiva, siplizumab, targeted therapy, ticilimumab, tositumomab
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(DA-koh-jen) A drug that is used to treat myelodysplastic syndromes and is being studied in the treatment of other types of cancer. It is a type of antimetabolite. Also called decitabine.
- Browse Related Terms: capecitabine, Dacogen, decitabine, deferasirox, docetaxel, Exjade, fluoropyrimidine, Taxotere, Xeloda
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An anticancer drug that is a type of antitumor antibiotic.
- Browse Related Terms: anticancer antibiotic, antineoplastic antibiotic, antitumor antibiotic, dactinomycin, DX-52-1, idarubicin, KRN5500, KW2189
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An isoflavone found in soy products. Soy isoflavones are being studied in the prevention of cancer.
- Browse Related Terms: biochanin A, daidzein, esterified estrogen, genistein, Glycine max, soy, soya, soybean
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(dul-TEP-uh-rin) A drug used to prevent blood clots from forming or to treat blood clots that have formed in patients with cancer or other conditions. Dalteparin is a type of anticoagulant. Also called dalteparin sodium and Fragmin.
- Browse Related Terms: anagrelide, anticoagulant, Arixtra, blood thinner, coumarin, dalteparin, dalteparin sodium, fondaparinux, fondaparinux sodium, Fragmin, Innohep, lepirudin, M-EDTA, minocycline-EDTA, pentoxifylline, platelet, thrombocyte, tinzaparin, tinzaparin sodium, urokinase
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(dul-TEP-uh-rin SOH-dee-um) A drug used to prevent blood clots from forming or to treat blood clots that have formed in patients with cancer or other conditions. Dalteparin sodium is a type of anticoagulant. Also called dalteparin and Fragmin.
- Browse Related Terms: anagrelide, anticoagulant, Arixtra, blood thinner, coumarin, dalteparin, dalteparin sodium, fondaparinux, fondaparinux sodium, Fragmin, Innohep, lepirudin, M-EDTA, minocycline-EDTA, pentoxifylline, platelet, thrombocyte, tinzaparin, tinzaparin sodium, urokinase
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A synthetic hormone that is a type of androgen and is used to treat endometriosis. It is being evaluated in the treatment of endometrial cancer.
- Browse Related Terms: antiprogestin, beta-endorphin, birth control pill, danazol, dexamethasone, hormone responsive, Megace, megestrol, Mifeprex, mifepristone, oral contraceptive pill, RU 486, steroid metabolism gene
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(dap-toh-MY-sin) A drug used to treat certain bacterial skin and bloodstream infections in adults. Daptomycin is also being studied in the treatment of fever and neutropenia (an abnormal decrease in the number of neutrophils, a type of white blood cell) in patients with cancer. It is a type of antibiotic. Also called Cubicin.
- Browse Related Terms: aminoglycoside antibiotic, amoxicillin, amoxicillin-clavulanate potassium, Augmentin, Cubicin, daptomycin, moxifloxacin, moxifloxacin hydrochloride
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(dar-be-POE-e-tin AL-fa) A substance made in the laboratory that stimulates the bone marrow to produce red blood cells. It belongs to the family of drugs called antianemics.
- Browse Related Terms: ABT-751, acitretin, alanosine, annamycin, atamestane, BAY 56-3722, BAY 59-8862, BBR 2778, BBR 3464, beta alethine, BL22 immunotoxin, budesonide, CC-8490, cevimeline, darbepoetin alfa, E7070, E7389, eflornithine, EP-2101, EPO906, epratuzumab, ERA-923, everolimus, gabapentin, GTI-2040, halofuginone hydrobromide, ibandronate, lometrexol, lutetium texaphyrin, MLN2704, MLN591DM1, modafinil, motexafin lutetium, nimustine, OGX-011, perifosine, perillyl alcohol, phenobarbital, phenylbutyrate, PI-88, pirfenidone, pixantrone, PV701, pyrazoloacridine, R-flurbiprofen, ravuconazole, rebeccamycin, retinyl palmitate, rhizoxin, RPR 109881A, SDX-102, SGN-00101, SJG-136, staurosporine, suramin, T900607, talotrexin, taurolidine, triamcinolone, trimetrexate glucuronate, ursodiol, velafermin, vitamin E, XRP9881, zileuton
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A microscope (device used to magnify small objects) in which objects are lit at a very low angle from the side so that the background appears dark and the objects show up against this dark background.
- Browse Related Terms: autoclave, dark-field microscope, dilator, electron microscope, laser, laser acupuncture, light microscope, medical device, microwave acupuncture, nebulizer, oxygen saturation test, penile implant, Sensor
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(da-SA-tih-nib) A drug used to treat certain types of chronic myeloid leukemia and acute lymphoblastic leukemia. Dasatinib is also being studied in the treatment of certain other blood diseases and types of cancer. Dasatinib binds to and blocks BCR-ABL and other proteins that help cancer cells grow. It is a type of tyrosine kinase inhibitor. Also called BMS-354825 and Sprycel.
- Browse Related Terms: BMS-354825, dasatinib, Gleevec, imatinib mesylate, nilotinib, Sprycel, STI571, Tasigna
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An impartial group that oversees a clinical trial and reviews the results to see if they are acceptable. This group determines if the trial should be changed or closed. Also called DSMB.
- Browse Related Terms: action study, agent study, Bias, chemoprevention study, clinical study, clinical trial, Data and Safety Monitoring Board, DSMB, endpoint, Gerson therapy, intervention group, maximum tolerated dose, mean survival time, median survival time, MTD, multicenter study, NCI clinical trials cooperative group, phase I trial, phase I/II trial, phase IV trial, placebo therapy, Quality of Life, schedule, sham therapy, single blind study, study agent, t test, unconventional cancer treatments