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Into or within a vein. I.V. usually refers to a way of giving a drug or other substance through a needle or tube inserted into a vein. Also called intravenous.
- Browse Related Terms: addiction, aerosolize, disulfiram, drug abuse, encephalopathy, euphoria, extract, generic, holmium Ho 166 DOTMP, I.V., medical castration, oltipraz, overdose, pharmacopoeia, phospholipid complex, potassium hydroxide, substance abuse
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A drug that is used to prevent and treat osteoporosis, and is being studied in the treatment of cancer that has spread to the bones. It belongs to the family of drugs called bisphosphonates.
- Browse Related Terms: ABT-751, acitretin, alanosine, annamycin, atamestane, BAY 56-3722, BAY 59-8862, BBR 2778, BBR 3464, beta alethine, BL22 immunotoxin, budesonide, CC-8490, cevimeline, darbepoetin alfa, E7070, E7389, eflornithine, EP-2101, EPO906, epratuzumab, ERA-923, everolimus, gabapentin, GTI-2040, halofuginone hydrobromide, ibandronate, lometrexol, lutetium texaphyrin, MLN2704, MLN591DM1, modafinil, motexafin lutetium, nimustine, OGX-011, perifosine, perillyl alcohol, phenobarbital, phenylbutyrate, PI-88, pirfenidone, pixantrone, PV701, pyrazoloacridine, R-flurbiprofen, ravuconazole, rebeccamycin, retinyl palmitate, rhizoxin, RPR 109881A, SDX-102, SGN-00101, SJG-136, staurosporine, suramin, T900607, talotrexin, taurolidine, triamcinolone, trimetrexate glucuronate, ursodiol, velafermin, vitamin E, XRP9881, zileuton
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Inherited bone marrow failure syndrome. A rare disorder in which a person's bone marrow is unable to make enough blood cells and there is a family history of the same disorder. There are several different inherited bone marrow failure syndromes. Patients with an IBMFS are at high risk of forming acute leukemia or certain solid tumors. Also called inherited bone marrow failure syndrome .
- Browse Related Terms: aplastic anemia, autologous bone marrow, bone marrow, bone marrow cancer, CD34 antigen, hematologic cancer, IBMFS, inherited bone marrow failure syndrome, myeloablation, myelodysplasia, myelodysplastic syndromes, myeloproliferative disorder, myelosuppression, nonhematologic cancer, nonmalignant hematologic disorder, polycythemia vera, severe myelosuppression, smoldering leukemia
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(ih-brih-TOO-moh-mab ty-oo-EKS-eh-tan) A monoclonal antibody that is used to treat certain types of B-cell non-Hodgkin lymphoma and is being studied in the treatment and detection of other types of B-cell tumors. Monoclonal antibodies are made in the laboratory and can locate and bind to substances in the body, including cancer cells. Ibritumomab binds to the protein called CD20, which is found on B cells. It is linked to the compound tiuxetan. This allows certain radioisotopes to be attached before it is given to a patient. It is a type of monoclonal antibody-chelator conjugate. Also called Zevalin.
- Browse Related Terms: ibritumomab tiuxetan, IDEC-Y2B8, In 111 ibritumomab tiuxetan, In 111 Zevalin, indium In 111 ibritumomab tiuxetan, radioimmunotherapeutics, technetium Tc 99m sulfur colloid, tracer, Y 90 ibritumomab tiuxetan, Y 90 Zevalin, yttrium Y 90 ibritumomab tiuxetan, Zevalin
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(I-byoo-PROH-fen) A drug used to treat fever, swelling, pain, and redness by preventing the body from making a substance that causes inflammation. It is a type of nonsteroidal anti-inflammatory drug (NSAID). Also called Advil and Motrin.
- Browse Related Terms: Advil, benzydamine, carbamide, choline magnesium trisalicylate, ibuprofen, Motrin, Naprosyn, naproxen, NCX 4016, nitric oxide-releasing acetylsalicylic acid derivative, sodium salicylate, Trilisate, urea
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At the time the World Health Organization's (WHO) International Agency for Research on Cancer (IARC) published their first monograph on Childhood Cancer in 1988, Dr. R. Marsden published an annex giving a classification scheme for childhood cancer that consisted of 12 groups based chiefly on histologic type. The classification by Marsden has been modified and is now called the International Classification of Childhood Cancers.
- Browse Related Terms: Collaborative Staging Algorithm, Extent of Disease, ICCC Classification, In situ cancer, Invasive Cancer, Malignant Cancer, primary tumor, Stage, Stage at Diagnosis
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A small device used to correct a heartbeat that is abnormal (too fast, too slow, or irregular). The device is placed by surgery in the chest or abdomen. Wires are passed through a vein to connect the device to the heart. When it detects abnormal heartbeats, it sends an electrical shock to the heart to restore the heartbeat to normal. Also called implantable cardioverter-defibrillator.
- Browse Related Terms: artificial pacemaker, cardiac pacemaker, EEG, electrode, electroencephalogram, ICD, implantable cardioverter-defibrillator, Lhermitte's sign, pacemaker, polysomnogram, surface electrode
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A drug used to treat certain types of breast cancer in postmenopausal women. It is also being studied in the treatment of other types of cancer. ICI 182780 blocks estrogen activity in the body and is a type of antiestrogen. Also called Faslodex and fulvestrant.
- Browse Related Terms: 4-hydroxytamoxifen, Aromasin, aromatase inhibitor, exemestane, Faslodex, Femara, fulvestrant, ICI 182780, letrozole, strontium ranelate
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An anticancer drug that stops tumor cells from growing by blocking the ability of cells to make DNA. It belongs to the family of drugs called thymidylate synthase inhibitors. Also called raltitrexed.
- Browse Related Terms: aminocamptothecin, aminoglutethimide, amsacrine, anastrozole, anhydrovinblastine, batimastat, BAY 12-9566, camptothecin, carboxyamidotriazole, CI-980, CPT 11, homoharringtonine, ICI D1694, IM-862, L-778,123, lonafarnib, lurtotecan, marimastat, MDL 101,731, mivobulin isethionate, nitrocamptothecin, pilocarpine, raltitrexed, ritonavir, saquinavir mesylate, SCH 66336, T138067, teniposide, vinblastine, vindesine, vinorelbine
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(I-duh-ROO-bih-sin) An anticancer drug that is a type of antitumor antibiotic. Also called 4-demethoxydaunorubicin.
- Browse Related Terms: anticancer antibiotic, antineoplastic antibiotic, antitumor antibiotic, dactinomycin, DX-52-1, idarubicin, KRN5500, KW2189
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A radiolabeled monoclonal antibody that is used to treat certain types of B-cell non-Hodgkin lymphoma and is being studied in the treatment of other types of B-cell tumors. It is made up of the monoclonal antibody ibritumomab plus the radioisotope yttrium Y 90. It binds to the protein called CD20, which is found on B cells. The radiation in the yttrium Y 90 may kill the cancer cells. IDEC-Y2B8 is a type of radiopharmaceutical. Also called Y 90 ibritumomab tiuxetan, Y 90 Zevalin, and yttrium Y 90 ibritumomab tiuxetan.
- Browse Related Terms: ibritumomab tiuxetan, IDEC-Y2B8, In 111 ibritumomab tiuxetan, In 111 Zevalin, indium In 111 ibritumomab tiuxetan, radioimmunotherapeutics, technetium Tc 99m sulfur colloid, tracer, Y 90 ibritumomab tiuxetan, Y 90 Zevalin, yttrium Y 90 ibritumomab tiuxetan, Zevalin
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Describes a disease of unknown cause.
- Browse Related Terms: anticachexia, bench-to-bedside, denomination, emetogenic, idiopathic, immunosuppressive, inoperable, latent, operable, orthotopic, postmortem, refractory, regional, translational research
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(IH-dee-oh-PA-thik MY-eh-loh-fy-BROH-sis) A progressive, chronic disease in which the bone marrow is replaced by fibrous tissue and blood is made in organs such as the liver and the spleen, instead of in the bone marrow. This disease is marked by an enlarged spleen and progressive anemia. Also called agnogenic myeloid metaplasia, chronic idiopathic myelofibrosis, myelosclerosis with myeloid metaplasia, and primary myelofibrosis.
- Browse Related Terms: agnogenic myeloid metaplasia, chronic idiopathic myelofibrosis, idiopathic myelofibrosis, myelofibrosis, myelosclerosis with myeloid metaplasia, primary myelofibrosis
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(IH-dee-oh-PA-thik noo-MOH-nyuh SIN-drome) A set of pneumonia-like symptoms (such as fever, chills, coughing, and breathing problems) that occur with no sign of infection in the lung. Idiopathic pneumonia syndrome is a serious condition that can occur after a stem cell transplant.
- Browse Related Terms: angioimmunoblastic T-cell lymphoma, dumping syndrome, gastric mucosal hypertrophy, giant hypertrophic gastritis, idiopathic pneumonia syndrome, Ménétrier disease, Richter syndrome, Richter transformation
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(IH-dee-oh-PA-thik THROM-boh-sy-toh-PEE-nik PUR-pyuh-ruh) A condition in which platelets (blood cells that cause blood clots to form) are destroyed by the immune system. The low platelet count causes easy bruising and bleeding, which may be seen as purple areas in the skin, mucous membranes, and outer linings of organs. Also called immune thrombocytopenic purpura and ITP.
- Browse Related Terms: erythroleukoplakia, erythroplakia, essential thrombocythemia, essential thrombocytosis, idiopathic thrombocytopenic purpura, immune thrombocytopenic purpura, ITP, leukoplakia, neoplasia, thrombocytopenia
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A drug that blocks the effects of estrogen.
- Browse Related Terms: antiestrogen, Evista, idoxifene, Nolvadex, raloxifene, raloxifene hydrochloride, selective estrogen receptor modulator, SERM, tamoxifen, tamoxifen citrate
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A drug that reduces the risk of cancer cell growth by interfering with the cells' DNA.
- Browse Related Terms: alkylating agent, cytarabine, deferoxamine, glycinamide ribonucleotide formyltransferase inhibitor, idoxuridine, MAGE-3, oncogene, p53 gene, ras gene, thymidylate synthase inhibitor, tributyrin
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A test to check for blood in the stool. A brush is used to collect water drops from around the surface of a stool while it is still in the toilet bowl. The samples are then sent to a laboratory, where they are checked for a human blood protein. Blood in the stool may be a sign of colorectal cancer. Also called immunoassay fecal occult blood test, immunochemical fecal occult blood test, and immunologic fecal occult blood test.
- Browse Related Terms: iFOBT, immunoassay fecal occult blood test, immunochemical fecal occult blood test, immunologic fecal occult blood test, neurological exam
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An anticancer drug that belongs to the family of drugs called alkylating agents.
- Browse Related Terms: Alkeran, altretamine, bizelesin, busulfan, carmustine, carzelesin, chlorambucil, cyclophosphamide, glufosfamide, ifosfamide, lomustine, mafosfamide, melphalan, mitolactol, penclomedine, procarbazine, sarCNU, sarcosinamide nitrosourea, semustine, streptozocin, Temodar, temozolomide, thiotepa, treosulfan, VNP40101M
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A monoclonal antibody linked to a toxic substance. It is being studied in the treatment of melanoma that has spread to distant parts of the body. IgG-RFT5-dgA is made in the laboratory. It can find and kill certain white blood cells that prevent the immune system from killing cancer cells. Also called RFT5-dgA immunotoxin.
- Browse Related Terms: anti-CD19 immunotoxin, anti-CD22 immunotoxin, anti-CD22 immunotoxin CAT-8015, anti-EpCAM-Pseudomonas-exotoxin fusion protein, B43-PAP immunotoxin, CAT-8015, erb-38 immunotoxin, huC242-DM4, IgG-RFT5-dgA, immunoglobulin, immunotoxin, LMB-1 immunotoxin, LMB-2 immunotoxin, LMB-7 immunotoxin, LMB-9 immunotoxin, maytansinoid DM4-conjugated humanized monoclonal antibody huC242, Proxinium, radioimmunotherapy, RFT5-dgA immunotoxin, VB4-845