A drug that may improve the response of cancer cells to chemotherapy.
- Browse Related Terms: allergen, Amanita phalloides, carcinoembryonic antigen peptide-1, child-life worker, complete remission, complete response, death cap, eosinophilia, evaluable patients, measurable disease, O(6)-benzylguanine, proteomic profile
- Browse Related Terms: adenocarcinoma, arsenic, cancer registry, EGFR inhibitors, extensive stage SCLC, large cell cancer, limited stage SCLC, oat cell, small cell lung cancer, squamous cell carcinoma
(oh-BAT-oh-klax MEH-zih-layt) A substance being studied in the treatment of several types of cancer. It is a form of obatoclax, which blocks the activity of certain proteins needed for cells to live and may cause tumor cells to die. It is a type of apoptosis inducer.
- Browse Related Terms: 852A, ABT-263, BI 2536, ispinesib, MK0752, Nipent, obatoclax mesylate, pentostatin, PT-100, RTA 744, SB-715992, SNX-5422, SNX-5422 mesylate, talabostat, talabostat mesylate, topoisomerase II inhibitor RTA 744, topoisomerase inhibitor
(oh-BEE-sih-tee) A condition marked by an abnormally high, unhealthy amount of body fat.
- Browse Related Terms: anterior, lipid, nipple, obese, Obesity, overweight, posterior
Also listed in:
An improvement that can be measured by the health care provider (for example, when a tumor shrinks or there are fewer cancer cells in the blood).
- Browse Related Terms: assessment, clinical breast exam, clinical practice guidelines, clinical researcher, clinician, electronic medical record, legal aid organization, living will, mineral, multidisciplinary, nutraceutical, objective improvement, patient advocate, primary care, primary care doctor, social service
(ub-JEK-tiv reh-SPONTS) A measurable response.
- Browse Related Terms: baseline, blood pressure, Brief Pain Inventory, disease-free survival, evaluable disease, gene expression, gram, kilogram, levels of evidence, milligram, milliliter, millimeter, nanogram, objective response, ounce, outcome, plastic surgery, sperm count (spurm kownt), subjective improvement, time to progression
(oh-blih-MER-sen) A substance being studied in the treatment of cancer. It may kill cancer cells by blocking the production of a protein that makes cancer cells live longer and by making them more sensitive to anticancer drugs. It is a type of antisense oligodeoxyribonucleotide. Also called augmerosen, bcl-2 antisense oligodeoxynucleotide G3139, and Genasense.
- Browse Related Terms: AEG35156, augmerosen, bcl-2 antisense oligodeoxynucleotide G3139, GEM640, Genasense, oblimersen, vascular endothelial growth factor-antisense oligonucleotide
(OB-ser-VAY-shun) Closely monitoring a patient's condition but withholding treatment until symptoms appear or change. Also called active surveillance, expectant management, and watchful waiting.
- Browse Related Terms: active surveillance, definitive treatment, early menopause, hypothesis, Observation, premature ovarian failure, primary ovarian insufficiency, surveillance
Also listed in:
A type of study in which individuals are observed or certain outcomes are measured. No attempt is made to affect the outcome (for example, no treatment is given).
- Browse Related Terms: 9-cis retinoic acid, amrubicin, brostallicin, dehydroepiandrosterone, DHEA, doxercalciferol, iododoxorubicin, lentinan, observational study, oncology, RevM10 gene, selenium, silymarin, valganciclovir
(ob-SEH-siv kum-PUL-siv dis-OR-der) An anxiety disorder in which a person has intrusive ideas, thoughts, or images that occur repeatedly, and in which he or she feels driven to perform certain behaviors over and over again. For example, a person may worry all the time about germs and so will wash his or her hands over and over again. Having an obsessive-compulsive disorder may cause a person to have trouble carrying out daily activities.
- Browse Related Terms: anesthetic, anxiety, bloating, chronic fatigue syndrome, GAD, general anesthesia, generalized anxiety disorder, inflammation, Inflammatory, lassitude, obsessive-compulsive disorder, palliation, palpitation, phantom limb pain, psychological, ritual, self-esteem, spinal cord compression, spirituality, VAS, visual analog scale
(ob-tun-DAY-shun) A dulled or reduced level of alertness or consciousness.
- Browse Related Terms: bone marrow transplantation, cryoablation, DNA replication, ejaculation, isolation, microcalcification, obtundation, ovulation, sun protection factor, transurethral needle ablation, transurethral radiofrequency ablation, tumor initiation, tumor promotion
(uh-KULT PRY-mayr-ee TOO-mer) Cancer in which the site of the primary (original) tumor cannot be found. Most metastases from occult primary tumors are found in the head and neck.
- Browse Related Terms: Alteration, bone marrow metastasis, bone metastasis, brain metastasis, central nervous system metastasis, CNS metastasis, distant metastasis, hematogenous, liver metastasis, localized, lung metastasis, metastasis, metastasize, metastatic, metastatic cancer, micrometastasis, nonmetastatic, occult primary tumor, primary tumor, staging
(uh-KULT ... KAN-ser) Cancer cells are found in sputum (mucus coughed up from the lungs), but no tumor can be found in the lung by imaging or bronchoscopy, or the primary tumor is too small to be assessed.
- Browse Related Terms: AIDS-related cancer, anal cancer, bone cancer, cervical cancer, cervix, colon cancer, eye cancer, gastric cancer, heart cancer, invasive cancer, invasive cervical cancer, kidney cancer, lung cancer, Merkel cell cancer, occult stage non-small cell lung cancer, oral cancer, peritoneal cancer, precancerous, precancerous polyps, prostate cancer, small intestine cancer, spindle cell cancer, stage I colorectal cancer, stage I esophageal cancer, stage I prostate cancer, stage I vaginal cancer, stage II vaginal cancer, stage III prostate cancer, stomach cancer, ulcer
A health professional trained to help people who are ill or disabled learn to manage their daily activities.
- Browse Related Terms: biochemist, dentist, dietary counseling, dietitian, enterostomal therapist, nurse, nutritional counseling, nutritionist, occupational therapist, prosthodontist, radiation nurse, registered dietitian, rehabilitation specialist, respiratory therapist, Specialist
A type of radionuclide scan used to find carcinoid and other types of tumors. Radioactive octreotide, a drug similar to somatostatin, is injected into a vein and travels through the bloodstream. The radioactive octreotide attaches to tumor cells that have receptors for somatostatin. A radiation-measuring device detects the radioactive octreotide, and makes pictures showing where the tumor cells are in the body. Also called somatostatin receptor scintigraphy and SRS.
- Browse Related Terms: 5-HT3 receptor antagonist, 5-hydroxytryptamine 3 receptor antagonist, Aloxi, Anzemet, dolasetron, dolasetron mesylate, granisetron, granisetron hydrochloride, Kytril, lerisetron, octreotide scan, ondansetron, ondansetron hydrochloride, palonosetron, palonosetron hydrochloride, SRS, talampanel, tropisetron, type 3 serotonin receptor antagonist, Zofran
(AH-kyoo-ler MEH-luh-NOH-muh) A rare cancer of melanocytes (cells that produce the pigment melanin) found in the eye. Also called intraocular melanoma.
- Browse Related Terms: albinism, dysplastic nevus, intraocular melanoma, iris, junctional nevus, MC1R, melanin, melanocortin 1 receptor, melanocyte, melanotropin receptor, mole, nevus, nonmelanomatous, ocular melanoma, pigment, pupil
(Ã¢ÂÂ¦ RAY-shee-oh) A measure of the odds of an event happening in one group compared to the odds of the same event happening in another group. In cancer research, odds ratios are most often used in case-control (backward looking) studies to find out if being exposed to a certain substance or other factor increases the risk of cancer. For example, researchers may study a group of individuals with cancer (cases) and another group without cancer (controls) to see how many people in each group were exposed to a certain substance or factor. They calculate the odds of exposure in both groups and then compare the odds. An odds ratio of one means that both groups had the same odds of exposure and, therefore, the exposure probably does not increase the risk of cancer. An odds ratio of greater than one means that the exposure may increase the risk of cancer, and an odds ratio of less than one means that the exposure may reduce the risk of cancer. Also called relative odds.
- Browse Related Terms: animal study, case-control study, control animal, hazard ratio, healthy control, odds ratio, phase II/III trial, phase III trial, placebo, primary endpoint, randomized clinical trial, relative odds, relative risk, retrospective study, risk ratio