Tolerance

A condition in which higher doses of a drug are required to produce the same effect achieved during initial use; often associated with physical dependence.

Incomplete resistance to a given biotic or abiotic stress. Tolerant genotypes are less inhibited by the stress, but are not immune.

A state of specific immunologic unreponsiveness. Individuals are normally tolerant to their own cells and tissues. Autoimmune diseases occur when tolerance fails.

The ability of a system to provide continuity of operation under various abnormal conditions.

The permissible range of variation of some characteristic from its nominal value.