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• A condition in which higher doses of a drug are required to produce the same effect achieved during initial use; often associated with physical dependence.

  National Institute on Drug Abuse - Cite This Source - This Definition
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  Cite Definition for Tolerance

  American Psychological Association (APA)

  Tolerance. (n.d.). NIH Prescription Drug Abuse Glossary. Retrieved June 9, 2023, from website: http://www.expertglossary.com/definition/tolerance.

  Chicago Manual of Style (CMS)

  Tolerance. www.drugabuse.gov. NIH Prescription Drug Abuse Glossary. National Institute on Drug Abuse. http://www.expertglossary.com/definition/tolerance (accessed: June 9, 2023).

  Modern Language Association (MLA)

  "Tolerance." NIH Prescription Drug Abuse Glossary. National Institute on Drug Abuse. 9 June. 2023 http://www.expertglossary.com/definition/tolerance.

• Browse Related Terms: addiction, central nervous system, Comorbidity, Dopamine, Norepinephrine, Physical Dependence, Stimulants, Tolerance, Withdrawal

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