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  • When researchers talk about vectors, often they are talking about insects, which as a group of invertebrate animals carry a host of different infectious agents. (However, a vector can be any living creature that transmits an infectious agent to humans.)

    Vectors may mechanically spread the infectious agent, such as a virus or parasite. In this scenario the vector—for instance a mosquito— contaminates its feet or proboscis ("nose") with the infectious agent, or the agent passes through its gastrointestinal tract. The agent is transmitted from the vector when it bites or touches a person. In the case of an insect, the infectious agent may be injected with the insect's salivary fluid when it bites. Or the insect may regurgitate material or deposit feces on the skin, which then enter a person's body, typically through a bite wound or skin that has been broken by scratching or rubbing.

    In the case of some infectious agents, vectors are only capable of transmitting the disease during a certain time period. In these situations, vectors play host to the agent. The agent needs the host to develop and mature or to reproduce (multiply) or both (called cyclopropagative). Once the agent is within the vector animal, an incubation period follows during which the agent grows or reproduces or both, depending on the type of agent. Only after this phase is over does the vector become infective. That is, only then can it transmit an agent that is capable of causing disease in the person.

  • Browse Related Terms: infection, report of a disease, reservoir, Vector, Vector-borne transmission, Virus, zoonotic disease or infection

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  • A virus is an extremely tiny infectious agent that is only able to live inside a cell. Basically, viruses are composed of just two parts. The outer part is a protective shell made of protein. This shell is often surrounded by another protective layer or envelope, made of protein or lipids (fats). The inner part is made of genetic material, either RNA or DNA. A virus does not have any other structures (called organelles) that living cells have, like a nucleus or mitochondria. These organelles are the tiny organs that maintain a cell's metabolism (life processes). A virus has no metabolism at all. Because a virus lacks organelles, it cannot reproduce by itself. To reproduce, a virus invades a cell within the body of a human or other creature, called the host. Each type of virus has particular types of host creatures and host cells that it will invade successfully. Once within the host cell, the virus uses the cell's own organelles to produce more viruses. In essence, the virus forces the cell to replicate the virus' own genetic material and protective shell. Once replicated, the new viruses leave the host cell and are ready to invade others.

  • Browse Related Terms: infection, report of a disease, reservoir, Vector, Vector-borne transmission, Virus, zoonotic disease or infection

All > Healthcare > Medicine > Malaria

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