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Asexual reproductive stage of malaria parasites. In red blood cells, schizogony entails development of a single trophozoite into numerous merozoites. A similar process happens in infected liver cells.
- Browse Related Terms: Erythrocytic stage, Exoerythrocytic stage, Hepatocytes, hepatomegaly, Hypnozoite, Larvae, Merozoite, Protozoan, Schizogony, Schizont, Sporozoite, Suppressive treatment, Trophozoite
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A developmental form of the malaria parasite that contains many merozoites. Schizonts are seen in the liver-stage and blood-stage parasites.
- Browse Related Terms: Erythrocytic stage, Exoerythrocytic stage, Hepatocytes, hepatomegaly, Hypnozoite, Larvae, Merozoite, Protozoan, Schizogony, Schizont, Sporozoite, Suppressive treatment, Trophozoite
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Morbid conditions following as a consequence of a disease.
- Browse Related Terms: Anopheles, Bacteria, Congenital malaria, etiology, immune system, infection, Parasite, pathogen, Resistance, Sequelae, Species, Vector, Vector competence
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The branch of science dealing with the measurement and characterization of antibodies and other immunological substances in body fluids, particularly serum.
- Browse Related Terms: anorexia, antibody, antigen, Coma, efficacy, Immunity, lymphocyte, Serology, Splenectomy, splenomegaly
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Organisms in the same genus that have similar characteristics.
- Browse Related Terms: Anopheles, Bacteria, Congenital malaria, etiology, immune system, infection, Parasite, pathogen, Resistance, Sequelae, Species, Vector, Vector competence
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Removal of the spleen.
- Browse Related Terms: anorexia, antibody, antigen, Coma, efficacy, Immunity, lymphocyte, Serology, Splenectomy, splenomegaly
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Enlargement of the spleen. Found in some malaria patients. Splenomegaly can be used to measure malaria endemicity during surveys (e.g., in communities or in schoolchildren).
- Browse Related Terms: anorexia, antibody, antigen, Coma, efficacy, Immunity, lymphocyte, Serology, Splenectomy, splenomegaly
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A stage in the life cycle of the malaria parasite. Sporozoites are produced in the mosquito and migrate to the mosquito's salivary glands. They can be inoculated into a human host when the mosquito takes a blood meal on the human. In the human, the sporozoites enter liver cells where they develop into the next stage of the malaria parasite life cycle (the liver stage or exo-erythrocytic stage).
- Browse Related Terms: Erythrocytic stage, Exoerythrocytic stage, Hepatocytes, hepatomegaly, Hypnozoite, Larvae, Merozoite, Protozoan, Schizogony, Schizont, Sporozoite, Suppressive treatment, Trophozoite
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The proportion of female anopheline mosquitoes of a particular species that have sporozoites in their salivary glands (as seen by dissection), or that are positive in immunologic tests to detect sporozoite antigens.
- Browse Related Terms: Enzyme-linked immunosorbent assay (ELISA), Gametocyte, Macrogametocyte, Microgametocyte, Monocyte, Oocyst, Sporozoite rate
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A drug used against malaria. Its value has been compromised by the emergence of drug-resistant malaria parasites
- Browse Related Terms: antibiotic, Antimicrobial agents, Antimicrobial resistance, Aralen, Chloroquine, Cryptic malaria, DEET, Diurnal, drug resistance, Fansidar, Halofantrine, Icterus, prophylaxis, Rigor, Sulfadoxine-pyrimethamine, vaccine
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Treatment intended to prevent clinical symptoms and parasitemia through destruction of parasites in red blood cells. It does not prevent infection because the parasite stages inoculated by the mosquito (sporozoites) will survive and invade the liver with the development of liver-stage parasites. It is when the parasites leave the liver cells to invade the blood that they are eliminated. Because the blood- stage parasites are the ones that cause disease, eliminating these stages will prevent symptoms.
- Browse Related Terms: Erythrocytic stage, Exoerythrocytic stage, Hepatocytes, hepatomegaly, Hypnozoite, Larvae, Merozoite, Protozoan, Schizogony, Schizont, Sporozoite, Suppressive treatment, Trophozoite