S1 mappingA method to characterise post-transcriptional modifications in RNA (removal of introns etc.
S1 nucleaseAn enzyme obtained from the filamentous fungus Aspergillus oryzae which specifically degrades RNA or single-stranded DNA into its constituent…
saccharifactionFollowing liquefaction, the hydrolysis of polysaccharides by glucoamylase to maltose and glucose.
Salivary gland(SA-lih-VAYR-ee gland) A gland in the mouth that produces saliva.
SalmonellaA genus of rod-shaped, gram-negative bacteria that are a common cause of food poisoning.
salt toleranceThe ability of a plant in soil or in culture to withstand a concentration of common salt (sodium chloride) which is damaging or lethal to most other…
Sanger sequencingA widely used method of determining the order of bases in DNA. See also: sequencing, shotgun sequencing
SAPFluid content of the xylem and phloem cells of plants. Fluid content of the vacuole generally referred to as cell sap.
saprophyteAn organism (generally a fungus) that depends on dead plant or animal tissue for its source of nutrition and metabolic energy.
satelliteA chromosomal segment that branches off from the rest of the chromosome but is still connected by a thin filament or stalk.
satellite DNAHighly repetitive DNA in plant and animal genomes, consisting of millions of copies of sequences typically in the range 5-500 bp long.
satellite RNAA small, self-splicing RNA molecule that accompanies several plant viruses, including tobacco ringspot virus. Synonym: viroid.
Satellite RNA (viroids)A small, self-splicing RNA molecule that accompanies several plant viruses, including tobacco ringspot virus.
ScaffoldThe central protein aceous core structure of condensed eukaryotic chromosomes. The scaffold is composed of non-histone chromosomal protein s.
Scale UpConversion of a process, such as fermentation of a micro-organism, from a small laboratory scale to a larger industrial scale.
scanning electron microscope(Abbreviation: SEM). An electron-beam-based microscope used to examine, in a three dimensional screen image, the surface structure of prepared specimens.
SCARAbbreviation for sequence characterized amplified region.
scarificationThe chemical or physical treatment given to certain seed s having hard, impermeable seed coats in order to puncture or weaken the seed coat sufficiently…
Schwann cellA type of glial cell of the peripheral nervous system that helps separate and insulate nerve cells.
scionA twig or bud used for grafting onto another plant or rootstock.
scion-stock interactionThe effect of a rootstock on a scion (and vice versa) in which a particular scion grafted onto a specific s performs differently than it would either on…
sclerenchymaA strengthening tissue in plants, composed of cells with heavily lignified cell walls.
SDS-PAGEAbbreviation for sodium dodecyl sulphate polyacrylamide gel electrophoresis.
secondary antibodyIn an ELISA or other immunological assay system, the antibody designed to bind to the primary antibody, and to which a label is generally attached.
secondary cell wallThe innermost layer of cell wall, giving rigidity to the cells. Characterized by its highly organized microfibrillar structure, and only formed in certain…
secondary growthType of growth characterized by an increase in the thickness of stem and root, and resulting from the formation of secondary s by the vascular cambium.
secondary immune responseThe rapid immune response that occurs during the second (and subsequent) encounters of the immune system of a mammal with a specific antigen.
secondary messengerA chemical compound within a cell that is responsible for initiating the response to a signal from a chemical messenger (such as a hormone) that cannot…
secondary metabolismThe production by living organisms of substances not essential for primary metabolic functions or physiology.
secretionThe transport of a molecule from the inside of a cell through the cell membrane.
SEEDBotanically, the matured ovule without accessory parts. Colloquially, anything which may be sown; i.e.
seed storage proteinsProteins accumulated in large amounts in protein bodies within seed s. They act as a source of amino acids during germination.
segment-polarity geneA gene that functions to define the anterior and posterior components of body segments in Drosophila.
segregantAn individual derived from a cross between two unlike parents.
segregationFor genes, the separation of allele pairs from one another and their resulting assortment into different cells at meiosis.
selectableHaving a gene product that, when present, enables the identification and preferential propagation of a particular genotype. See: reporter gene.
Selectable markerA gene whose expression allows one to identify cells that have been transforrned or transfected with a vector containing the marker gene.
selection1. Differential survival and reproduction of phenotypes . 2. A system for either isolating or identifying specific genotypes in a mixed population.
selection coefficientA measure of the intensity of selection at a locus, commonly abbreviated as s. It represents the proportionate reduction in the gametic contribution of a…
selection cultureA selection based on difference(s) in environmental conditions or in culture medium composition, such that preferred variant cells or cell lines…
selection differentialThe difference between the mean of the individuals selected to be parents and the mean of the overall population; it represents the average superiority of…
selection pressureThe intensity of selection acting on a population of organisms or on cells in culture.
selection responseThe difference between the mean of the individuals selected to be parents and the mean of their offspring.
Selective breedingMaking deliberate crosses or matings of organisms so the offspring will have a desired characteristic derived from one of the parents.
self-incompatibilityIn plants, the inability of the pollen to fertilize ovules (female gametes) of the same plant.
Self-pollinationPollen of one plant is transferred to the female part of the same plant or another plant with the same genetic makeup.
self-replicating elementsExtrachromosomal DNA elements that have origins of replication for the initiation of their own DNA synthesis.
semi-conservative replicationDuring DNA duplication, each strand of a parent DNA molecule acts as a template for the synthesis of a new complementary strand.
semi-continuous cultureCells in an actively dividing state which are maintained in culture by periodically draining off the medium and replenishing it with fresh medium.
semi-permeable membraneA natural or synthetic material which selectively allows the passage of certain ions or molecules.
semi-sterilityThe condition of partial fertility. Often associated with chromosomal aberrations or the result of mutagenesis.
Semiconservative replicationDuring DNA duplication, each strand of a parent DNA molecule is a template for the synthesis of its new complementary strand.
senescenceA late stage in the development of multicellular organisms, during which irreversible loss of function and degradation of biological components occur.
sense RNAThe RNA transcript of the coding strand DNA (often represented as the (+)-strand). Opposite: antisense RNA.
SensitivityWhen referring to a medical test, sensitivity refers to the percentage of people who test positive for a specific disease among a group of people who have…
sepsis(SEP-sis) The presence of bacteria or their toxins in the blood or tissues.
septate(SEP-tate) An organ or structure that is divided into compartments.
septumA dividing wall or partition, which splits a structure into separate cells or compartments.
sequenceThe linear order of nucleotides along a DNA or RNA molecule, and the process of obtaining this.
Sequence assemblyA process whereby the order of multiple sequenced DNA fragments is determined.
sequence characterized amplified region(Abbreviation: SCAR). A molecular marker obtained by the conversion to a sequence-tagged site of a single random amplified polymorphic DNA product.
sequence divergenceThe percent difference in the nucleotide sequence between related nucleic acid sequences, or in the amino acid sequence in a comparison between related…
Sequence hypothesisFrancis Crick's seminal concept that genetic information exists as a linear DNA code; DNA and protein sequence are colinear.
Sequence tagged site (STS)A unique (single-copy) DNA sequence used as a mapping landmark on a chromosome.
sequence-tagged site(Abbreviation: STS). Short unique DNA sequence (200-500 bp long) that can be amplified by PCR and is thus tagged to the site on the chromosome from which…
SequencingDetermination of the order of nucleotides (base sequences) in a DNA or RNA molecule or the order of amino acids in a protein.
Sequencing technologyThe instrumentation and procedures used to determine the order of nucleotides in DNA.
serial divisionSplitting of excised shoot-tip material growing in vitro, in order to induce the development of greater numbers of plantlets.
serial float cultureA technique whereby immature anthers are floated on a liquid medium, and continue their development through to the release of pollen.
SerologyThe branch of science dealing with the measurement and characterization of antibodies and other immunological substances in body fluids, particularly…
serumThe clear liquid part of the blood that remains after blood cells and clotting proteins have been removed.
serum albuminThe main protein in blood plasma. Low levels of serum albumin occur in people with malnutrition, inflammation, and serious liver and kidney disease.
severe combined immunodeficiency (SCID)A disease affecting the immune system. SCID is fatal if affected individuals do not receive bone marrow transplants. See also antibody
sewage treatmentA widespread biotechnological processes in developed economies. Methods vary widely, but all are designed for the biological break-down of human and…
sex chromosomeDifferentiated chromosome which is responsible for the determination of sex of the individual.
sex determinationAny method by which the distinction between males and females is established in a species, particularly at an early stage of foetal development.