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(⦠MEH-thul-d-TRIP-toh-fan) A substance being studied in the treatment of melanoma and many other types of cancer. 1-methyl-d-tryptophan blocks the breakdown of the amino acid tryptophan, which is needed for T cells (a type of immune system cell) to kill tumor cells. Giving 1-methyl-d-tryptophan to patients who have received chemotherapy for cancer may help kill more tumor cells. It is a type of enzyme inhibitor and immunosuppressant. Also called D-1MT.
- Browse Related Terms: 1-methyl-d-tryptophan, Actinex, D-1MT, EM-1421, masoprocol, NDGA, nordihydroguaiaretic acid, Se-methyl-seleno-L-cysteine, tetra-O-methyl NDGA, tetra-O-methyl nordihydroguaiaretic acid
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A substance that is being studied in the treatment of cancer. It belongs to the family of drugs called folate analogs.
- Browse Related Terms: 10-propargyl-10-deazaaminopterin, 17-dimethylaminoethylamino-17-demethoxygeldanamycin, AP23573, BMS-188797, iloprost, paricalcitol, PSC 833, seocalcitol, SL-11047, Telcyta, TLK286, vapreotide, ZD0473
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(... toh-poh-TEE-kan) A substance being studied in the treatment of certain types of cancer, including ovarian cancer and lung cancer. 11C topotecan is a radioactive form of the anticancer drug topotecan. It builds up in tumor tissues and is detected by positron emission tomography (PET). It may be used to help determine whether treatment with topotecan will work. It is a type of topoisomerase I inhibitor.
- Browse Related Terms: 11C topotecan, 18F-FLT, 3'-deoxy-3'-(18F) fluorothymidine, EF5, fluorine F 18 EF5, fluorothymidine F 18, technetium Tc 94m sestamibi
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(12-oh-TEH-truh-DEK-uh-noyl-FOR-bol-13- A-suh-TAYT) A substance being studied in the treatment of hematologic cancers. It is a type of phorbol ester. Also called TPA.
- Browse Related Terms: 12-O-tetradecanoylphorbol-13-acetate, adverse effect, alkalinization, analog, CA-125, cancer antigen 125, Carcinogen, Compound, implant, laxative, lubricant, Myelin, odorant, technetium Tc 99m dextran, TPA, vitamin K, YKL-40
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A liquid that has been promoted as a treatment for a wide range of diseases, including cancer. The ingredients thought to be in 126-F have been tested, and none of them has been shown to be effective in treating any form of cancer. 126-F is not available in the United States. Also called Cancell, Cantron, Crocinic Acid, Jim's Juice, JS-101, JS-114, Protocel, and Sheridan's Formula.
- Browse Related Terms: 126-F, Cancell, Cantron, Crocinic Acid, heterogeneous, Jim's Juice, JS-101, JS-114, Protocel, Sheridan's Formula
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(... REH-tih-NOH-ik A-sid) A drug that is used in the treatment of acne and psoriasis and is being studied in cancer prevention. It is a type of retinoid. Also called isotretinoin.
- Browse Related Terms: 13-cis retinoic acid, all-trans retinoic acid, ATRA, folate, folic acid, glutamic acid, isotretinoin, L-glutamic acid, retinoic acid, tretinoin, Vesanoid, vitamin A acid
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A radioactive substance that is used in imaging tests, and is being studied in the treatment of cancer. It is a type of radiopharmaceutical. Also called iodine I 131 metaiodobenzylguanidine .
- Browse Related Terms: 131I-MIBG, 4-nitroquinoline 1-oxide, 4-NQO, azoxymethane, ferumoxytol, iodine I 131 metaiodobenzylguanidine, N-butyl-N-(4-hydroxybutyl) nitrosamine, preclinical study, strontium
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A substance being studied in the treatment of cancer. It is made from an antibiotic called geldanamycin. 17-AAG helps cause the breakdown of certain proteins in the cell, and may kill cancer cells. It is a type of antineoplastic antibiotic and a type of HSP90 inhibitor. Also called 17-N-allylamino-17-demethoxygeldanamycin and tanespimycin.
- Browse Related Terms: 17-AAG, 17-N-allylamino-17-demethoxygeldanamycin, maribavir, OPT-80, PAR-101, tanespimycin, tiacumicin B
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(17-dy-MEH-thul-uh-MEE-noh-EH-thul-uh-MEE-noh-17-dee-meh-THOK-see-gel-DAN-uh-MY-sin) 17-DMAG. A substance that is being studied in the treatment of cancer. It belongs to the family of drugs called geldanamycin analogs.
- Browse Related Terms: 10-propargyl-10-deazaaminopterin, 17-dimethylaminoethylamino-17-demethoxygeldanamycin, AP23573, BMS-188797, iloprost, paricalcitol, PSC 833, seocalcitol, SL-11047, Telcyta, TLK286, vapreotide, ZD0473
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(17-N-A-lul-uh-MEE-noh-17-DEE-meh-THOK-sih-gel-DAN-uh-MY-sin) A substance being studied in the treatment of cancer. It is made from an antibiotic called geldanamycin. 17-N-allylamino-17-demethoxygeldanamycin helps cause the breakdown of certain proteins in the cell, and may kill cancer cells. It is a type of antineoplastic antibiotic and a type of HSP90 inhibitor. Also called 17-AAG and tanespimycin.
- Browse Related Terms: 17-AAG, 17-N-allylamino-17-demethoxygeldanamycin, maribavir, OPT-80, PAR-101, tanespimycin, tiacumicin B
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A substance that is being studied in positron emission tomography (PET) imaging to detect tumor hypoxia (a low level of oxygen in the tumor).This may help predict how the tumor will respond to treatment. It belongs to the family of drugs called radiopharmaceuticals. Also called fluorine F 18 EF5.
- Browse Related Terms: 18F-EF5, Amplimexon, beclomethasone, BG00001, CpG 7909, denileukin diftitox, hydroxychloroquine, imexon, iodine I 131 tositumomab, methoxsalen, mitoxantrone, Novantrone, Ontak, PF-3512676, ProMune, QS21, Virulizin, visilizumab
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A radioactive substance being studied in the diagnosis of cancer. 18F-FLT is injected into the blood and builds up in cells that are dividing, including cancer cells. The radiation that it gives off as it decays (breaks down) helps make clear pictures of tumors during positron emission tomography (PET) scans. It is a type of radiopharmaceutical. Also called 3'-deoxy-3'-(18F) fluorothymidine and fluorothymidine F 18.
- Browse Related Terms: 11C topotecan, 18F-FLT, 3'-deoxy-3'-(18F) fluorothymidine, EF5, fluorine F 18 EF5, fluorothymidine F 18, technetium Tc 94m sestamibi
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(â¦-FLOOR-oh-MY-soh-NID-uh-sole) A radioactive substance being studied as an imaging agent in head and neck cancers and other types of cancer. It binds to large molecules in tumor cells that have a low level of oxygen. Radiation given off by 18F-fluoromisonidazole is detected by a PET scan. The amount of 18F-fluoromisonidazole in the tumor may help decide the best treatment and help predict whether the cancer will come back after treatment. 18F-fluoromisonidazole is a type of radioimaging agent. Also called 18F-MISO and FMISO.
- Browse Related Terms: 18F-fluoromisonidazole, 18F-MISO, F-18 16 alpha-fluoroestradiol, F-18 FES, fluorine F 18 FEQA, FMISO, yttrium Y 90 DOTA-tyr3-octreotide, yttrium Y 90 edotreotide, yttrium Y 90 SMT 487
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A radioactive substance being studied as an imaging agent in head and neck cancers and other types of cancer. It binds to large molecules in tumor cells that have a low level of oxygen. Radiation given off by 18F-MISO is detected by a PET scan. The amount of 18F-MISO in the tumor may help decide the best treatment and help predict whether the cancer will come back after treatment. 18F-MISO is a type of radioimaging agent. Also called 18F-fluoromisonidazole and FMISO.
- Browse Related Terms: 18F-fluoromisonidazole, 18F-MISO, F-18 16 alpha-fluoroestradiol, F-18 FES, fluorine F 18 FEQA, FMISO, yttrium Y 90 DOTA-tyr3-octreotide, yttrium Y 90 edotreotide, yttrium Y 90 SMT 487
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(... NOO-klee-er mag-NEH-tik REH-zoh-nants SPEK-troh-SKAH-pik IH-muh-jing) A noninvasive imaging method that provides information about cellular activity (metabolic information). It is used along with magnetic resonance imaging (MRI) which provides information about the shape and size of the tumor (spatial information). Also called magnetic resonance spectroscopic imaging, MRSI, and proton magnetic resonance spectroscopic imaging.
- Browse Related Terms: 1H-nuclear magnetic resonance spectroscopic imaging, contrast material, gadolinium, gadopentetate dimeglumine, Gd-DTPA, isointense, magnetic resonance perfusion imaging, magnetic resonance spectroscopic imaging, Magnevist, MRSI, perfusion magnetic resonance imaging, proton magnetic resonance spectroscopic imaging
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2ME2. A drug that prevents the formation of new blood vessels that tumors need in order to grow. It is derived from estrogen and belongs to the family of drugs called angiogenesis inhibitors.
- Browse Related Terms: 2-methoxyestradiol, AE-941, AG3340, Angiozyme, BMS-275291, CC-1088, CC-5013, CP-547,632, lenalidomide, prinomastat, Revlimid, RPI.4610, squalamine lactate, TAC-101, thalidomide, Thalomid
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(⦠MAH-noh-KLOH-nul AN-tih-BAH-dee â¦) A substance being studied in the treatment of cancer. It is made by linking a monoclonal antibody called 170, which binds to the protein MUC-1, to a substance called 2IT-BAD, which binds radioactive substances. 2IT-BAD monoclonal antibody 170 may be used to detect cancer cells and kill them. It is a type of immunoconjugate.
- Browse Related Terms: 2IT-BAD monoclonal antibody 170, 90Y-DOTA-biotin, capromab pendetide, CC49-streptavidin, indium In 111 DOTA monoclonal antibody HuAFP31, ProstaScint, ProstaScint scan, streptavidin, yttrium Y 90, yttrium Y 90 DOTA monoclonal antibody HuAFP31, yttrium Y 90 DOTA monoclonal antibody HuPAM4, yttrium Y 90 DOTA-biotin
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A substance being studied in the treatment of cancer. It is a type of ribonucleotide reductase inhibitor. Also called 3-AP and Triapine.
- Browse Related Terms: 3-aminopyridine-2-carboxaldehyde thiosemicarbazone, 3-AP, BCX-1777, forodesine, forodesine hydrochloride, Triapine
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A substance being studied in the treatment of cancer. It is a type of ribonucleotide reductase inhibitor. Also called 3-aminopyridine-2-carboxaldehyde thiosemicarbazone and Triapine.
- Browse Related Terms: 3-aminopyridine-2-carboxaldehyde thiosemicarbazone, 3-AP, BCX-1777, forodesine, forodesine hydrochloride, Triapine
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A graphic display of depth, width, and height. Also called 3-dimensional.
- Browse Related Terms: 3-D, 3-dimensional, DNA gene-expression microarray, fiberoptic, FISH, fluorescence in situ hybridization, liquid-based Pap test