HMG-CoA reductase inhibitor

(HMG-koh-EN-zime-A ree-DUK-tayz in-HIH-bih-ter) A substance that blocks an enzyme needed by the body to make cholesterol and lowers the amount of cholesterol in the blood. HMG-CoA reductase inhibitor drugs are called statins. Also called hydroxymethylglutaryl-coenzyme A reductase inhibitor.