prostaglandin-endoperoxide synthase 2

(PROS-tuh-GLAN-din-EN-doh-peh-ROK-side SIN-thayz) An enzyme that speeds up the formation of substances that cause inflammation and pain. It may also cause tumor cells to grow. Some tumors have high levels of prostaglandin-endoperoxide synthase 2 and blocking its activity may reduce tumor growth. Also called COX-2 and cyclooxygenase-2.