tumor vasculature-targeted tumor necrosis factor alpha

(TOO-mer VAS-kyoo-luh-chur-TAR-geh-ted TOO-mer neh-KROH-sis FAK-ter AL-fuh) A substance being studied in the treatment of cancer. It is made by linking tumor necrosis factor (TNF) to a peptide. The peptide binds to tumor blood vessels, and TNF damages them. It is a type of biological response modifier. Also called NGR-TNF.