Clostridium Difficile(klah-STRIH-dee-um dih-FIS-ih-lee) A type of bacterium found in human and animal waste.
Clostridium Difficile InfectionA bacterium that is one of the most common causes of infection of the colon in the US. Patients taking antibiotics are at risk of becoming infected with C.
CMLA slowly progressing disease in which too many white blood cells (not lymphocytes) are made in the bone marrow.
CMMLA slowly progressing type of myelodysplastic/myeloproliferative disease in which too many myelomonocytes (a type of white blood cell) are in the bone…
CMVA virus that may be carried in an inactive state for life by healthy individuals.
cnicin(NIH-sin) A substance found in certain plants, including blessed thistle. It has been used in some cultures to treat certain medical problems.
CNSThe brain and spinal cord. Also called central nervous system.
CNS DepressantsA class of drugs that slow CNS function (also called sedatives and tranquilizers), some of which are used to treat anxiety and sleep disorders; includes…
CNS metastasis(...meh-TAS-tuh-sis) Cancer that has spread from the original (primary) tumor to the central nervous system (CNS).
CNS PNETA type of cancer that arises from a particular type of cell within the brain or spinal cord.
CNS prophylaxis(...pro-fih-LAK-sis) Chemotherapy or radiation therapy given to the central nervous system (CNS) as a preventive treatment.
CNS sanctuary therapy(...SANK-choo-wayr-ee THAYR-uh-pee) Chemotherapy or radiation therapy given to the central nervous system (CNS) as a preventive treatment.
CNS tumorA tumor of the central nervous system (CNS), including brain stem glioma, craniopharyngioma, medulloblastoma, and meningioma.
CNTO 328A chimeric (made from human and mouse proteins) monoclonal antibody being studied in the treatment of advanced kidney cancer and other types of cancer.
co-cultureA mixture of two or more different kinds of cells that are grown together.
Co-morbidityThe presence of one or more diseases or disorders in addition to a primary disease or disorder.
co-trimoxazoleA drug used in the treatment of infections caused by bacteria and protozoa. It is a combination of two anti-infection drugs, sulfamethoxazole and…
coactivated T cellA T cell that has been coated with monoclonal antibodies to enhance its ability to kill tumor cells.
cobalamin(koh-BAL-uh-min) A vitamin that is needed to make red blood cells and DNA (the genetic material in cells) and to keep nerve cells healthy.
cobalt 60A radioactive form of the metal cobalt, which is used as a source of radiation to treat cancer.
coccyx(KOK-six) The small bone at the bottom of the spine. It is made up of 3-5 fused bones. Also called tailbone.
Cockayne syndromeA genetic condition characterized by short stature, premature aging, sensitivity to light, and possibly deafness and mental retardation.
codeine(KOH-deen) A drug made from opium or morphine that is used to relieve pain and to prevent coughing and diarrhea. Codeine is a type of opiate.
codeine phosphate(KOH-deen FOS-fayt) A drug made from opium or morphine that is used to relieve pain and to prevent coughing and diarrhea.
coenzyme Q10A substance found in most tissues in the body, and in many foods. It can also be made in the laboratory.
coffee enema(KAW-fee EH-nuh-muh) The injection of coffee through the anus into the colon (large intestine).
cognition(kog-NIH-shun) The mental process of thinking, learning, remembering, being aware of surroundings, and using judgment.
cohort(koh-HORT) A group of individuals who share a common trait, such as birth year.
cohort studyA research study that compares a particular outcome (such as lung cancer) in groups of individuals who are alike in many ways but differ by a certain…
COL-3A substance being studied in the treatment of cancer. COL-3 may block tumor growth by preventing the growth of new blood vessels needed for tumors to grow.
COL18A1A substance being studied in the treatment of cancer. COL18A1 is made from a type of collagen (a protein found in cartilage and other connective tissue).
cold noduleWhen radioactive material is used to examine the thyroid with a scanner, nodules that collect less radioactive material than the surrounding thyroid…
colectomy(koh-LEK-toh-mee) An operation to remove all or part of the colon. When only part of the colon is removed, it is called a partial colectomy.
CollaborationPeople or groups working together to achieve a common goal.
Collaborative Staging AlgorithmA joint effort by several organizations to develop standard computerized methods for determining the stage of cancer based on tumor size, extension of the…
collagenA fibrous protein found in cartilage and other connective tissue.
collagen diseaseA term previously used to describe chronic diseases of the connective tissue (e.g.
collagenaseA type of enzyme that breaks down the protein collagen.
collecting ductThe last part of a long, twisting tube that collects urine from the nephrons (cellular structures in the kidney that filter blood and form urine) and…
coloanal anastomosisA surgical procedure in which the colon is attached to the anus after the rectum has been removed. Also called coloanal pull-through.
coloanal pull-throughA surgical procedure in which the colon is attached to the anus after the rectum has been removed. Also called coloanal anastomosis.
Colon(KOH-lun) The longest part of the large intestine, which is a tube-like organ connected to the small intestine at one end and the anus at the other.
colon cancer(KOH-lun KAN-ser) Cancer that forms in the tissues of the colon (the longest part of the large intestine).
colon crypt(KOH-lun KRIPT) Tube-like gland found in the lining of the colon and rectum. Colon crypt cells renew the lining of the intestine and make mucus.
colon polyp(KOH-lun PAH-lip) An abnormal growth of tissue in the lining of the bowel. Polyps are a risk factor for colon cancer.
Colonoscope(koh-LAH-noh-SKOPE) A thin, tube-like instrument used to examine the inside of the colon.
Colonoscopy(KOH-luh-NOS-koh-pee) Examination of the inside of the colon using a colonoscope, inserted into the rectum.
colony-stimulating factor(KAH-luh-nee-STIM-yoo-LAY-ting FAK-ter) A substance that stimulates the production of blood cells.
Colorectal(KOH-loh-REK-tul) Having to do with the colon or the rectum.
colorectal cancer(KOH-loh-REK-tul KAN-ser) Cancer that develops in the colon (the longest part of the large intestine) and/or the rectum (the last several inches of the…
colostomy(koh-LOS-toh-mee) An opening into the colon from the outside of the body. A colostomy provides a new path for waste material to leave the body after part…
Colostrum(kuh-los'trum) the thin, yellow, milky fluid secreted by the mammary gland before or after delivery of an infant.
colposcope(KOL-puh-SKOPE) A lighted magnifying instrument used to examine the vagina and cervix.
colposcopy(kol-POSS-koh-pee) Examination of the vagina and cervix using a lighted magnifying instrument called a colposcope.
Coma(KOH-muh) A condition in which a patient is in a state of deep sleep and cannot be awakened.
combination chemotherapy(KOM-bih-NAY-shun KEE-moh-THAYR-uh-pee) Treatment using more than one anticancer drug.
combretastatin A4 phosphate(kum-BREE-tuh-STA-tin ⦠FOS-fayt) A substance being studied in the treatment of cancer.
comedo carcinomaA type of ductal carcinoma in situ (very early-stage breast cancer).
Comedocarcinoma(koh-mee'-do car sih no mah) is a type of Ductal Carcinoma In Situ in which some of the cancers cells in the duct begin to die and break down (degenerate).
comfort careCare given to improve the quality of life of patients who have a serious or life-threatening disease.
common bile ductA tube or vessel in the body that carries bile from the liver and gallbladder into the duodenum (the upper part of the small intestine).
Community Acquired InfectionAn infection that occurs without exposure in recent weeks or months to the risk from care in a hospital, clinic, doctor’s office, or home-care treatment…
Community Based Dental Partnership Program (CBDPP)(CBDPP)The program within the HRSA HIV/AIDS Bureau's Division of Community Based Programs that delivers HIV/AIDS dental care while simultaneously training dental…
Community Forum or Public MeetingA small-group method of collecting information from community members in which a community meeting is used to provide a directed but highly interactive…
Community-based Organization (CBO)(CBO)An organization that provides services to locally defined populations, which may or may not include populations infected with or affected by HIV disease.
ComorbidityThe condition of having two or more diseases at the same time.
CompanyThe company (also called applicant or sponsor) submits an application to FDA for approval to market a drug product in the United States.
comparative anatomy(kum-PAYR-uh-tiv uh-NA-toh-mee) The comparison of the structure (anatomy) of one animal or plant with the structure of a different animal or plant.
compassionate use trialA way to provide an investigational therapy to a patient who is not eligible to receive that therapy in a clinical trial, but who has a serious or…
complement protein(KOM-pleh-ment PROH-teen) One of a group of about 20 proteins that is found in the blood and is important in fighting infections and other diseases.
complementary and alternative medicine(KOM-pleh-MEN- tuh-ree... all-TER-nuh-tiv MEH-dih-sin) Forms of treatment that are used in addition to (complementary) or instead of (alternative)…
complementary medicine(KOM-pleh-MEN-tuh-ree MEH-dih-sin) Practices often used to enhance or complement standard treatments.
complete blood countA test to check the number of red blood cells, white blood cells, and platelets in a sample of blood. Also called blood cell count and CBC.
complete hysterectomy(kum-PLEET HIS-teh-REK-toh-mee) Surgery to remove the entire uterus, including the cervix. Also called total hysterectomy.
complete metastasectomy(... meh-TAS-tuh-SEK-toh-mee) Surgery to remove all metastases (tumors formed from cells that have spread from the primary tumor).
complete remissionThe disappearance of all signs of cancer in response to treatment. This does not always mean the cancer has been cured. Also called complete response.
complete response(kum-PLEET reh-SPONTS) The disappearance of all signs of cancer in response to treatment. This does not always mean the cancer has been cured.
compliance(kum-PLY-ants) The act of following a medical regimen or schedule correctly and consistently, including taking medicines or following a diet.
ComplicationA medical problem that occurs during a disease or after a procedure or treatment.
Compound(KOM-pownd) In science, a substance that is made up of more than one ingredient.
compound nevus(KOM-pownd NEE-vus) A type of mole formed by groups of nevus cells found in the epidermis and dermis (the two main layers of tissue that make up the skin).
Comprehensive PlanningThe process of determining the organization and delivery of HIV services. This strategy is used by planning bodies to improve decision-making about…
compression bandageA bandage designed to provide pressure to a particular area.
compression pump(kum-PREH-shun â¦) A machine used to keep blood and lymph flowing by pushing air through bands or sleeves that are placed on the arms or legs.
compulsion(kum-PUL-zhun) An uncontrollable urge to say or do something without an obvious reason.
computed tomographic colonography(kum-PYOO-ted toh-muh-GRA-fik KOH-lun-AH-gruh-fee) A procedure in which a detailed picture of the colon is created by an x-ray machine linked to a…
Computed Tomography(kom pyoo' ted to-mog' ruh fee) (CT Scan) the recording of internal body images at a predetermined plane by means of the tomograph.
computed tomography colography(kum-PYOO-ted toh-MAH-gruh-fee koh-LAH-gruh-fee) A method under study to examine the colon by taking a series of x-rays (called a CT scan) and using a…
computed tomography scan(kum-PYOO-ted toh-MAH-gruh-fee skan) A series of detailed pictures of areas inside the body taken from different angles.
computerized axial tomography scan(kum-PYOO-teh-RIZED AK-see-ul toh-MAH-gruh-fee skan) A series of detailed pictures of areas inside the body taken from different angles.
computerized tomography(kum-PYOO-teh-RIZED toh-MAH-gruh-fee) A series of detailed pictures of areas inside the body taken from different angles.
conception(kun-SEP-shun) In biology, the beginning of pregnancy, marked by fertilization of an egg by a sperm.
concurrent therapy(kun-KER-ent THAYR-uh-pee) A treatment that is given at the same time as another.
conditioned response(kun-DIH-shund reh-SPONTS) A type of learning in which repeated exposure to something may affect a person's behavior when they encounter an unrelated…
conditioned stimulusA situation in which one signal, or stimulus, is given just before another signal.
conditioning regimen(con-DIH-shuh-ning REH-jih-men) The treatments used to prepare a patient for stem cell transplantation (a procedure in which a person receives blood stem…