primary structureThe linear sequence of residues making up a polymer such as a nucleic acid, polysaccharide or protein.
primary tissueA tissue that has differentiated from a primary meristem.
primary transcriptThe RNA molecule produced by transcription prior to any post-transcriptional modifications; also called a pre-mRNA in eukaryotes.
PrimerA short DNA or RNA fragment annealed to single-stranded DNA, from which DNA polymerase extends a new DNA strand to produce a duplex molecule.
primer walkingA method for sequencing long (>1 kbp) cloned pieces of DNA. The initial sequencing reaction reveals the sequence of the first few hundred nucleotides of…
Primitive streakThe initial band of cells from which the embryo begins to develop. The primitive streak establishes and reveals the embryo's head-tail and left-right…
Primordial germ cellA gamete, that is, a sperm or egg, OR a primordial cell that can mature into a sperm or egg.
primordiumA group of cells which gives rise to an organ.
primosomeA protein -replication complex that catalyses the initiation of synthesis of Okazaki fragments during discontinuous replication of DNA.
Prion-related protein (PrP)A normal protein, expressed in the nervous system of animals, whose structure when altered (by interaction with altered copies of itself) is the cause of…
PrivacyIn genetics, the right of people to restrict access to their genetic information.
pro-embryoA group of cells arising from the division of the fertilized egg cell or somatic embryo before those cells which are to become the embryo are recognizable.
pro-meristemThe embryonic meristem that is the source of organ initials or foundation cells.
pro-nuclear micro-injectionAn early, low success-rate method to achieve transgenesis in animals, involving the micro-injection of many gene copies into one of the two pro-nuclei of…
pro-nucleusEither one of the two haploid gamete nuclei, just prior to their fusion in the fertilized egg.
pro-phageThe genome of a bacteriophage integrated into the chromosome of a lysogenic bacterial cell, and replicated along with its host chromosome.
pro-toxinA latent, non-active precursor form of a toxin.
ProbabilityThe chance that an event occurs. It is usually expressed as a percent. Zero percent denotes impossibility, while 100% denotes certainty.
probandThe individual in a family in whom an inherited trait is first identified.
ProbeA sequence of DNA or RNA, labeled or marked with a radioactive isotope, used to detect the presence of complementary nucleotide sequences. See Nucleotide.
procambiumA primary meristem that gives rise to primary vascular tissues and, in most woody plants, to the vascular cambium.
processed pseudo-geneA copy of a functional gene which has no promoter, no introns and which, consequently, is not itself transcribed.
production environmentAll input-output relationships, over time, at a particular location. The relationships include biological, climatic, economic, social, cultural and…
production traitsCharacteristics of animals, such as the quantity or quality of the milk, meat, fibre, eggs, work, etc.
productivityThe amount of economically significant product generated within a given period of time from a specified quantity of resource.
Progenitor cellA progenitor cell, often confused with stem cell, is an early descendant of a stem cell that can only differentiate, but it cannot renew itself anymore.
progenyOffspring; the product of reproduction or replication.
progeny testingWith respect to discrete loci, the inference of the allelic state of an individual from the pattern of segregation among its offspring.
progesterone(proh-JES-tuh-RONE) A type of hormone made by the body that plays a role in the menstrual cycle and pregnancy.
programmed cell deathA type of cell death in which a series of molecular steps in a cell leads to its death.
ProkaryoteA bacterial cell lacking a true nucleus; its DNA is usually in one long strand. See Eukaryote.
prolactin(proh-LAK-tin) A hormone that is made by the pituitary gland (a pea-sized organ in the center of the brain).
ProliferationIncrease by frequent and repeated reproduction; growth by cell division.
PromoterAny person who, directly or indirectly, organizes or assists in the organization of a tax shelter or who participates in the sale of any interests in a…
Pronuclear injectionThe use of a fine needle to inject DNA into the nucleus of an unfertilized egg.
PronucleusEither of the two haploid gamete nuclei just prior to their fusion in the fertilized ovum.
proofreadingThe scanning of newly-synthesized DNA for structural defects, such as mis-matched base pairs. A functional activity of most DNA polymerase s.
propagationThe duplication of a whole plant from a range of vegetative materials; adapted for in vitro culture as micropropagation.
propaguleAny structure capable of giving rise to a new plant by asexual or sexual reproduction, including bulbils, leafbuds, etc.
prophaseThe first stage of nuclear division. The stage during which occurs in the first division of meiosis (see: leptonema, zygonema, pachynema, diplonema…
prostate cancer(PROS-tayt KAN-ser) Cancer that forms in tissues of the prostate (a gland in the male reproductive system found below the bladder and in front of the…
protamineA class of small basic proteins that replace the histones in the chromosomes of some sperm cells.
proteaseAn enzyme that cleaves peptide bonds that link amino acids in protein molecules.
protein(PRO-teen) A molecule made up of amino acids that are needed for the body to function properly.
protein crystallizationThe production of a pure preparation of a protein. In this form, the three-dimensional structure of the molecule can be determined.
protein engineeringGenerating proteins with modified structures that confer novel properties such as higher catalytic specificity or thermal stability.
Protein kinaseAn enzyme that adds phosphate groups to a protein molecule at serine, threonine, or tyrosine residues.
protein metabolic stepOne step in the chain of reactions that take place in an organism and dictate the composition of that organism.
protein sequencingThe process of determining the amino acid sequence of a protein. Usually achieved following initially partial hydrolysis of the protein into smaller…
protein synthesisThe creation of proteins from their constituent amino acid s, in accordance with the encoding gene DNA sequence.
proteinaceous infectious particleBelieved to be the agent responsible for the class of diseases called spongiform encephalopathies, including scrapie in sheep, bovine spongiform…
Proteinaceous infectious particle (prion)A proposed pathogen composed only of protein with no detectable nucleic acid and which is responsible for Creutzfeldt-Jakob disease and kuru in humans and…
protoplasmThe essential, complex living substance of cells, upon which all vital functions of nutrition, secretion, growth and reproduction depend.
protoplastA bacterial or plant cell for which the cell wall has been removed either chemically or enzymatically, leaving its cytoplasm enveloped by a peripheral…
protoplast cultureThe culturing in vitro of plant protoplast s. Where protoplasts can be regenerated into whole plants, they represent an attractive target for genetic…
protoplast fusionThe induced or spontaneous coalescence of two or more protoplast s of the same or different species origin.
pseudo-affinity chromatographyA chromatographic technique in which a ligand is immobilized selectively to retain enzymes or other protein s.
pseudo-autosomal regionA section at one end of the X and Y chromosomes for which there is sufficient homology that there is synapsis between them during meiosis.
pseudocarpA fruit that incorporates, in addition to the ovary wall, other parts of the flower, such as the receptacle (e.g. strawberry). Synonym: false fruit.
pseudogeneAn incomplete or mutated copy of a gene which is not transcribed because it lacks a continuous open reading frame.
Pseudomonas spp.A widely distributed Gram-negative bacterial genus. Many of the soil forms produce a pigment that fluoresces under ultraviolet light, hence the…
psychrophileA micro-organism that can grow at temperatures below 30 °C and as low as 0 °C. See: mesophile, thermophile.
PUCA widely used expression plasmid containing a -galactosidase gene. (See Plasmid.)
pulsed-field gel electrophoresis(Abbreviation: PFGE). A procedure used to separate very large (50 kbp to several Mbp) DNA molecules by alteRNA ting the direction of electric current in a…
punctuated equilibriumThe occurrence of speciation events in bursts, separated by long intervals of species stability.
pure lineA strain in which all members are genetically nearly identical and are indistinguishable by phenotype.
PurineA double-ring, nitrogen-containing base present in nucleic acids . Adenine (A) and guanine (G) are the two purines normally present in DNA and RNA…
PVAThe Plant Variety Act. See U.S. Department of Agriculture.
PvPPlayer vs. Player. This means for one player to attack another player.
pyrethrinsActive constituents of pyrethrum (Tanacetum cinerariifolium) flowers, used as insecticides.
PyrimidineA single-ring, nitrogen-containing base present in nucleic acid s. Cytosine (C) and thymine (T) are present in DNA, whereas uracil (U) replaces T in RNA.
pyrogenBacterial substance that causes fever in mammals.
pyrophosphateA phosphate ion dimer; may be released on hydrolysis of ATP.