Maternal gene productA product in the male organism of a gene from the X chromosome.
maternal inheritanceInheritance controlled by non-nuclear genes (e.g. mitochrondria, chloroplast ) that are transmitted only through the female line.
matric potentialA water potential component, always of negative value, resulting from the presence of solid (often finely divided) surfaces; primarily responsible for…
MCSAbbreviation for multiple cloning site. See: polylinker.
MDAAbbreviation for multiple drop array. See: microdroplet array.
MeanA statistics term. The average value in a set of measurements. The mean is the sum of a set of numbers divided by how many numbers are in the set.
MediaAny organization in the business of informing the public with news or commentary.
medianA statistics term. The middle value in a set of measurements.
medium(pl.: media) 1. In plant tissue culture, a term for the liquid or solid formulation upon which plant cells, tissues or organs develop.
medium formulationIn tissue culture, the particular constituents for the culture medium, commonly comprising macro- and micro-elements, vitamins, plant hormones, and a…
mega yeast artificial chromosomeA yeast artificial chromosome (YAC) which can carry particularly large inserts (up to 1Mbp) - standard YACs typically carry inserts of up to 500kbp.
megabase(Abbreviation: Mb). A length of DNA consisting of 106 bases.
Megabase (Mb)Unit of length for DNA fragments equal to 1 million nucleotides and roughly equal to 1 cM. See also: centimorgan
Megabase cloningThe cloning of very large DNA fragments. (See Cloning.)
megaDalton(Abbreviation: MDa). One megaDalton is equal to 106 Dalton.
megagametophyteThe female gametophyte; the plant that develops from a megaspore.
megasporeThe female gametophyte in heterosporous plants. Synonym: macrospore.
MeiosisA special form of cell division in which each daughter cell receives half the amount of DNA as the parent cell.
meiotic analysisThe use of patterns of chromosome pairing at meiotic prophase and metaphase to detect relationships between chromosomes, from which can be deduced the…
meiotic driveAny mechanism that causes a particular allele or chromosome to be over-represented in a population of gametes.
melanin(MEH-luh-nin) A pigment that gives color to skin and eyes and helps protect it from damage by ultraviolet light.
Melanocyte(mel-AN-o-site) A cell in the skin and eyes that produces and contains the pigment called melanin.
melanoma(MEH-luh-NOH-muh) A form of cancer that begins in melanocytes (cells that make the pigment melanin).
melting temperature(Abbreviation: Tm). The temperature at which a double-stranded DNA molecule denatures into separate single strands.
membrane bioreactorA vessel in which cells are cultured on or behind a permeable membrane, which allows the diffusion of nutrients to the cells, but retains the cells…
memoryData storage in the form of chips, or the actual chips used to hold data; storage is used to describe memory that exists on tapes or discs.
memory cellLong-lived B cells and T cells that mediate rapid secondary immune responses to a previously encountered antigen.
Memory cellsA subset of antigen-specific T or B cells that "recall" prior exposure to an antigen and respond quickly without the need to be activated again by CD4…
Mendel's LawsTwo laws summarizing Gregor Mendel's theory of inheritance. The Law of Segregation states that each hereditary characteristic is controlled by two…
Mendel, Johann (Gregor)Austrian biologist, born in 1822 and died in 1884, who laid the foundations for the science of genetics.
Mendelian inheritanceManner in which genes and traits are passed from parents to children. Examples of Mendelian inheritance include autosomal dominant, autosomal recessive…
Mendelian populationA natural, interbreeding unit of sexually reproducing plants or animals sharing a common gene pool.
mericlinalRefers to a chimera with tissue of one genotype partly surrounded by that of another genotype.
mericloningA propagation method using shoot tips in culture to proliferate multiple buds, which can then be separated, rooted and planted out.
meristeleThe branch of a stele supplying the leaf.
meristemUndifferentiated but determined plant tissue, in which the cells are capable of active division and differentiation into specialized tissues such as…
meristem cultureA tissue culture containing meristematic dome tissue without adjacent leaf primordia or stem tissue.
meristem tipAn explant comprising the meristem (meristematic dome) and usually one pair of leaf primordia.
meristem tip cultureCultures derived from meristem tip explants . Used widely to achieve virus elimination and axillary shoot proliferation, less commonly for callus…
meristemoidA localized group of callus cells, characterized by their accumulation of starch, RNA and protein, and giving rise to adventitious shoots or roots.
merozygotePartial zygote produced by a process of partial genetic exchange, such as transformation in bacteria.
Mesemchymal stem cellAlso known as bone marrow stromal cells, mesenchymal stem cells are rare cells, mainly found in the bone marrow, that can give rise to a large number of…
Mesenchymal stem cellsCells from the immature embryonic connective tissue. A number of cell types come from mesenchymal stem cells, including chondrocytes, which produce…
Mesenchymal stem cells (MSCs)Cells from the immature embryonic connective tissue. A number of cell types come from mesenchymal stem cells, including chondrocytes, which produce…
Messenger RNA (mRNA)The class of RNA molecules that copies the genetic information from DNA, in the nucleus, and carries it to ribosomes, in the cytoplasm, where it is…
metabolic cellA cell that is not dividing. See: metabolism
metabolism(meh-TA-boh-lih-zum) The total of all chemical changes that take place in a cell or an organism.
metabolite(meh-TA-boh-lite) A substance made or used when the body breaks down food, drugs or chemicals, or its own tissue (for example, fat or muscle tissue).
metabolomicsThe large-scale study of the full complement of secondary metabolites produced by a given species in all its tissues and growth stages.
metacentric chromosomeA chromosome in which the centromere is located in the middle and, consequently, the chromosome arms are of about equal length.
Metachromatic leukodystrophyA heritable metabolic disorder, usually of infancy, characterized by myelin loss and other abnormalities of the white matter of the nervous system…
metal affinity chromatographyA chromatographic technique, in which a compound interacting with a specific metal ion can be captured by immobilizing the relevant ion on the column's…
metalloenzymeAn enzyme which requires the presence of a metal in order to be catalytically active.
MetallothioneinA protective protein that binds heavy metals, such as cadmium and lead.
MetaphaseStage of mitosis or meiosis (following prophase and preceding anaphase ) during which the chromosome s, or at least the kinetochores, lie in the central…
metastasis(meh-TAS-tuh-sis) The spread of cancer from one part of the body to another. A tumor formed by cells that have spread is called a "metastatic tumor" or a…
methylationThe addition of a methyl group (-CH3) to a molecule, most commonly in the context of DNA where cytosine and, less often, adenine residues can be modified…
MHCAbbreviation for major histocompatibility complex.
micro-arrayA large set of cloned DNA molecules immobilized as a compact and orderly pattern of sub-microlitre spots onto a solid matrix (typically a glass slide).
micro-carrierSmall particles used as a support material for (particularly mammalian) cells, which are too fragile to be pumped and stirred as bacterial cells are in a…
micro-elementA nutritional element required in very small quantities.
micro-encapsulationA process of enclosing a substance in very small sealed capsules from which material is released by heat, solution or other means.
micro-environmentA small-scale environment in which the conditions (temperature, humidity, pH etc.
micro-injectionThe introduction of small amounts of (usually) liquid material (DNA, RNA, enzyme s, cytotoxic agents) into a defined tissue or single cell with a fine…
micro-isolating systemMechanical separation of single cells or protoplasts thus allowing them to proliferate individually.
micro-organismOrganism visible only under magnification.
microalgal cultureCulture in bioreactors of microalgae (including seaweeds).
MicroarraySets of miniaturized chemical reaction areas that may also be used to test DNA fragments, antibodies, or proteins.
microarray technologyA new way of studying how large numbers of genes interact with each other and how a cell's regulatory networks control vast batteries of genes…
microbodyA frequently spherical cellular organelle, bound by a single membrane, 20-60 nm in diameter, and containing a variety of enzymes.
microdroplet array(Abbreviation: MDA). A technique used to simultaneously evaluate large numbers of media modifications, employing small quantities of medium into which are…
MicroenvironmentThe molecules and compounds such as nutrients and growth factors in the fluid surrounding a cell in an organism or in the laboratory, which play an…
microfibrilMicroscopic fibres visible only at the high magnification of the electron microscope.
micropropagationMiniaturized in vitro multiplication and/or regeneration of plant material under aseptic and controlled environmental conditions.
micropyle1. A small opening in the surface of a plant ovule through which the pollen tube passes prior to fertilization. 2.
microsatelliteA short sequence of DNA, usually 1 to 4 basepairs (a unit of DNA), that is repeated together in a row along the DNA molecule.
microsporeThe immature male gametophyte in seed plants; the haploid male cell that ripens into a pollen grain.
microtuberMiniature tuber, produced in tissue culture, which is readily regenerable into a normal tuberous plant.
MicrotubuleSelf-assembling components of the cytoskeleton. Microtubules are cylindrical protein polymers, interconnected by cross-bridging proteins, which…