micro-array

A large set of cloned DNA molecules immobilized as a compact and orderly pattern of sub-microlitre spots onto a solid matrix (typically a glass slide). Used to analyse patterns of gene expression, presence of markers, or nucleotide sequence. The major advantage of micro-arrays is the extent to which the process of genotyping can be automated, thereby enabling large numbers of individuals to be simultaneously genotyped at many loci. A similar approach may be used with other immobilized components for other purposes. Synonym: chip or DNA chip . See: somatic cell hybrid panel, radiation hybrid cell panel