KanamycinAn antibiotic of the aminoglycoside family that poisons translation by binding to the ribosomes.
kanrKanamycin resistance gene. (See Selectable marker.)
kappa chainOne of two classes of antibody light chains. The other is a lambda chain.
karyogamyThe fusion of nuclei or nuclear material that occurs at fertilization during sexual reproduction.
karyogramA diagrammatic representation of the full chromosome set of a species, highlighting characteristic physical features of individual chromosomes.
karyokinesisThe division of a cell nucleus. See: meiosis; mitosis.
KaryotypeAll of the chromosomes in a cell or an individual organism, visible through a microsope during cell division.
KBAbbreviation for kilobase (of single-stranded nucleic acid).
kbpAbbreviation for kilobase pairs (of double-stranded DNA ).
kcatThe catalytic rate constant that characterizes an enzyme-catalysed reaction. The larger the kcat value, the faster the conversion of substrate into…
kcat/KmThe catalytic efficiency of an enzyme-catalysed reaction. The greater the value of kcat/Km, the more rapidly and efficiently the substrate is converted…
KdAbbreviation for dissociation constant. Describes the strength of binding (or affinity) between molecules and their ligands . See: avidity.
kDaAbbreviation for kiloDalton. A unit of molecular mass equal to 1000 Dalton.
killer T cellT cells that kill cells displaying recognized antigens.
kilobase(Abbreviation: kb). A length of single-stranded nucleic acid composed of 1000 bases.
kilobase pairs(Abbreviation: kbp). A length of double-stranded DNA composed of 1000 base pairs.
kinaseAn enzyme that catalyses the transfer of a phosphate group from a high energy state (as in ATP) to another molecule.
kineticsDynamic processes involving motion. Often used as a suffix to indicate studies involving movement or rates of reactions.
kinetochoreStructure at the centromere of eukaryotic chromosomes. The kinetochore consists of inner and outer electron dense plates and a central zone containing…
kinetosomeGranular cytoplasmic structure which forms the base of a cilium or flagellum. Synonym: basal body.
kininA substance promoting cell division. In plant systems, the prefix cyto- has been added (cytokinin ) to distinguish it from kinin in animal systems.
Klenow fragmentA truncated form of DNA polymerase I from E. coli, used extensively for the production of synthetic DNA molecules as it retains polymerase and…
KmA dissociation constant that characterizes the binding of an enzyme to a substrate.
Knock InReplacement of a gene by a mutant version of the same gene using homologous recombination.
Knock OutInactivation of a gene by homologous recombination following transfection with a suitable DNA construct.
knockoutA mutant individual, in which a single functional gene has been replaced by a non-functional form of the gene.