HPrefix used to designate the human form of an enzyme. For example, hGH is human growth hormone.
habituationThe phenomenon whereby, after a number of sub-cultures, cells can grow without the addition to the tissue culture medium of previously obligatory factors.
haemoglobinProtein containing iron, located in erythrocytes of vertebrates; important for the transportation of oxygen to the cells of the body.
haemolymphThe mixture of blood and other fluids in the body cavity of an invertebrate.
haemophiliaA sex-linked hereditary bleeding disorder in which it takes a long time for the blood to clot and abnormal bleeding occurs.
hairpin loopA region in one strand of a polynucleotide which, due to an inverted repeat in the sequence, may under appropriate conditions fold back on itself and form…
hairy root cultureA culture consisting of highly branched roots of a plant. A plant tissue is treated with the bacterium Agrobacterium rhizogenes containing the Ri plasmid…
hairy root diseaseA disease of broad-leaved plants, where a proliferation of root-like tissue is formed from the stem.
halophyteA plant species adapted to soils containing a concentration of salt that is toxic to most plant species. See: salt tolerance.
haptenA small molecule, which by itself is not an antigen, but which as a part of a larger structure when linked to a carrier protein, can serve as an antigenic…
haptoglobinA serum protein that interacts with haemoglobin during recycling of the iron molecule of haemoglobin. Synonym: alpha globulin.
hardening offAdapting glasshouse or controlled environment grown plants to outdoor conditions by reducing availability of water, lowering the temperature, increasing…
Hardy-Weinberg equilibriumThe frequencies of genotypes at a locus resulting from random mating at that locus; for two alleles, A1 and A2, with respective frequencies in a…
HarvestingThe process of retrieving or collecting electronic data from storage media or devices; an EDiscovery vendor harvests electronic data from computer hard…
heat shock protein(... PROH-teen) One of a group of proteins that help protect cells from stresses such as heat, cold, and low amounts of oxygen or glucose (sugar).
helixA structure with a spiral shape. The normal state of double-stranded DNA is in the form of a double helix.
helminthA class of parasitic worms, especially those which are internal parasites of man and animals.
helper cellT cells that assist in stimulating B and T lymphocyte s to develop into antibody-producing plasma cells and killer T cells, respectively.
helper plasmidA plasmid that provides a function or functions to another plasmid in the same cell.
helper T cellA type of white blood cell that helps stimulate immune system reactions. Helper T cells help activate cytotoxic T cells and macrophages by secreting…
helper virusA virus that provides a function or functions to another virus in the same cell.
hemicellulaseAn enzyme that catalyses the degradation of hemicellulose.
hemicelluloseAny cellulose-like carbohydrate, but excluding cellulose itself. Together with pectin and lignin, hemicelluloses form the cell wall matrix.
HemizygousThe condition in which genes are present only once in the genotype and not in pairs.
hemoglobin(HEE-moh-GLOH-bin) The substance inside red blood cells that binds to oxygen in the lungs and carries it to the tissues.
herbicide resistanceThe ability of a plant to remain unaffected by the application of a herbicide.
Herbicide-tolerant cropCrop plants that have been developed to survive application(s) of one or more commercially available herbicides by the incorporation of certain gene(s)…
heredityResemblance among individuals related by descent; transmission of traits from parents to offspring.
heritabilityThe degree to which a given trait is controlled by inheritance, as opposed to being controlled by non-genetic factors.
hermaphrodite1. An animal that has both male and female reproductive organs, or a mixture of male and female attributes. 2.
heteroalleleA gene having mutations at two or more different sites.
HeterochromatinDark-stained regions of chromosomes thought to be for the most part genetically inactive.
HeteroduplexA double-stranded DNA molecule or DNA-RNA hybrid, where each strand is of a different origin.
heteroduplex analysisThe use of the electrophoretic mobility of to estimate the degree of non-homology between the sequences of the two strands.
heterogameticProducing unlike gametes with regard to the sex chromosomes. In mammals, the XY male is heterogametic, and the XX female is homogametic.
heterogeneous nuclear RNA(Abbreviation: hnRNA ). Large RNA molecules, which are found in the nucleus of a eukaryotic cell and the precursors of mRNA and other RNA molecules.
Heterogeneous nuclear RNA (hnRNA)The name originally given to large RNA molecules found in the nucleus, which are now known to be unedited mRNA transcripts, or pre-mRNAs. (See RNA.)
heterokaryonA cell with two or more different nuclei as a result of cell fusion. See: synkaryon.
heteroplasmyA condition in which two genetically different organelles are present in the same cell. The equivalent to heterozygous in the context of nuclear genes.
heteroploidCells with nuclei containing chromosome numbers other than diploid.
heteropyknosisThe property of certain chromosomes, or of their parts, to remain more dense during the cell cycle and to stain more intensely than other chromosomes or…
heterotrophOrganism non capable of self-nourishment utilizing carbon dioxide or carbonates as the sole source of carbon and obtaining energy from radiant energy or…
histoglobulinThe peptides present on the surface of nucleate cells, responsible for the differences between genetically non-identical individuals that cause rejection…
histology(his-TAH-loh-jee) The study of tissues and cells under a microscope.
histoneA type of protein found in chromosomes. Histones bind to DNA, help give chromosomes their shape, and help control the activity of genes.
HLAOne of a group of proteins found on the surface of white blood cells and other cells that play an important part in the body's immune response to foreign…
hollow fibreA tube of porous material, with an internal diameter of a fraction of a millimetre, making its ratio of surface area to internal volume very large.
holometabolousAn insect that undergoes complete metamorphosis to the adult from a morphologically distinct larval stage.
HomeoboxA highly conserved 180 bp DNA sequence that controls body part-, organ- or tissue-specific gene expression, most particularly involved in segmentation in…
homeotic genesGenes that act in concert to determine fundamental patterns of development.
homeotic mutationA mutation that causes a body part to develop in an inappropriate position in an organism, such as the mutation in Drosophila melanogaster that causes…
homoalleleOne of a number of otherwise identical alleles which differ at the same site in their sequence.
homodimerA protein comprising two identical polypeptide chains, or a dimer of identical residues.
homoduplex DNAA double-stranded fully complementary DNA molecule.
homoeologousReferring to chromosome s which are descended from a common progenitor, but which have evolved to be no longer fully homologous.
homogameticProducing similar gametes with regard to the sex chromosomes . In mammals, the female is homogametic (XX), and the male is heterogametic (XY).
homogenotizationAn allele replacement technique, in which a bacterial cell is transformed with a plasmid containing an altered copy of the target sequence, and a double…
homokaryonA cell with two or more identical nuclei as a result of fusion. Opposite: heterokaryon.
HomologIn diploid organisms, one member of a pair of matching chromosomes.
Homologous1. General definition: from the same source, or having the same evolutionary function or structure. 2.
Homologous chromosomesChromosomes that have the same linear arrangement of genes--a pair of matching chromosomes in a diploid organism. See Chromosomes.
Homologous recombinationThe exchange of DNA fragments between two DNA molecules or chromatids of paired chromosomes (during crossing over) at the site of identical nucleotide…
Homology1. The degree of identity between individuals, or characters. 2. The degree of identity of sequence (nucleotide or amino acid) between a number of DNA or…
homomultimerA protein consisting of a number of identical subunits.
homoplasmyThe condition in which all copies of an organelle in a cell are genetically identical. Opposite: heteroplasmy.
homopolymerA polymer (nucleic acid, polypeptide, etc.) which contains only one kind of residue (e.g. the polynucleotide GGGGGGGGG...).
Horizontal gene transferTransmission of DNA between species, involving close contact between the donor's DNA and the recipient, uptake of DNA by the recipient, and stable…