labelThe FDA approved label is the official description of a drug product which includes indication (what the drug is used for); who should take it; adverse…
Labeling of foodsThe process of developing a list of ingredients contained in foods. Labels imply that the list of ingredients can be verified. The U.S.
labellingThe process of attaching or inserting a label into a molecule. Most often in the context of nucleic acids or protein s.
lactoseA type of sugar found in milk and milk products.
Lag phaseThe initial growth phase, during which cell number remains relatively constant prior to rapid growth. See growth phase.
lagging strandThe strand of DNA that is synthesized discontinuously during replication (because DNA synthesis can proceed only in the 5'?3' direction).
lambda chainOne of two classes of antibody light chains. The other is a kappa chain.
lambda phageA bacteriophage that infects E. coli, commonly used as a cloning vector. See: integration-excision region.
lamellaA structure, plate or vesicle that is formed by two membranes lying parallel to each other.
laminar air-flow cabinetCabinet designed for cell or tissue culture manipulations requiring a sterile environment.
laminarinA storage polysaccharide of the brown algae.
lampbrush chromosomeLarge diplotene chromosomes present in oocyte nuclei, and particularly conspicuous in amphibians.
landraceIn plant genetic resources, an early, cultivated form of a crop species, evolved from a wild population, and generally composed of a heterogeneous mixture…
latent agentA pathogen, usually a virus, present in a host organism without producing any symptoms.
latent budAn inactive bud not held back by rest or dormant period, but which may start growth if stimulated.
leader sequenceA variable length sequence of nucleotides at the 5' end of an mRNA molecule that precedes the AUG initiation codon where translation begins and is not…
leading strandThe strand of DNA that is synthesized continuously during replication.
leaf bladeThe usually flattened portion of the leaf.
leaf bud cuttingA cutting that includes a short section of stem with attached leaf.
leaf primordiumA lateral outgrowth from the apical meristem, which will become a leaf when fully developed and expanded.
leaf rollA symptom of some virus diseases, characterized by curling of the leaves. Can also occur as a response to water stress.
leaf scarMark left on a stem after leaf abscission.
leafletExpanded leaf-like part of a compound leaf.
leaky mutantA mutant in which the gene product still retains some biological activity.
lectinA complex molecule that has both protein and sugars. Lectins are able to bind to the outside of a cell and cause biochemical changes in it.
LegumeA member of the pea family that possesses root nodules containing nitrogen-fixing bacteria.
leptonemaStage in meiosis immediately preceding synapsis and post DNA replication, in which the chromosomes appear as single, fine, threadlike structures.
Leukocyte(LOO-koh-site) A white blood cell. Refers to a blood cell that does not contain hemoglobin.
libraryA collection of cells, usually bacteria or yeast, that have been transformed with recombinant vectors carrying DNA inserts from a single species.
life cycleThe sequence of events from a given developmental stage in one generation to the same stage in the following generation.
ligandA small molecule (e.g. activators, substrates and inhibitors of enzyme activity) bound to a protein by non-covalent forces; an ion or a molecule that…
Ligase (DNA ligase)An enzyme that catalyzes a condensation reaction that links two DNA molecules via the formation of a phosphodiester bond between the 3' hydroxyl and 5'…
ligase chain reaction(Abbreviation: LCR). A technique for the detection and amplification of target DNA sequences.
LigateThe process of joining two or more DNA fragments.
ligate, ligationThe joining of two linear double-stranded DNA fragments by the formation of phosphodiester bonds.
lignificationThe thickening and strengthening of a plant cell wall with lignin.
ligninA group of high-molecular-weight amorphous polymers of phenylpropanoid compounds, giving strength to certain tissues. A major component of wood.
lignocelluloseThe combination of lignin, hemicellulose and cellulose that forms the structural framework of plant cell walls.
LineageA chart that traces the flow of genetic information from generation to generation.
linear phaseThe growth phase during cell culture when cell number increases arithmetically. The linear phase follows a period of exponential growth.
linearized vectorA covalently closed circular DNA vector (typically a plasmid ) which has been opened by restriction digestion to convert it to a linear molecule.
linkageThe frequency of coinheritance of a pair of genes and/or genetic markers, which provides a measure of their physical proximity to one another on a…
lipofectionDelivery into eukaryotic cells of DNA, RNA or other compounds that have been encapsulated in liposomes.
lipopolysaccharide(Abbreviation: LPS). A compound containing lipid bound to a polysaccharide; often a component of microbial cells walls.
liposome(LY-puh-some) A very tiny, fat-like particle that is made in the laboratory. In medicine, liposomes containing drugs or other substances are used in the…
LiposomesMembrane-bound vesicles constructed in the laboratory to transport biological molecules.
LiquefactionEnzymatic digestion (often by alpha-amylase) of gelatinized starch to form lower molecular weight polysaccharides.
liquid mediumCulture solution, without a solidifying agent, for in vitro cell growth.
liquid membraneThin films made up of liquids (as opposed to solids) which are stable in another liquid (usually water).
liquid nitrogenNitrogen gas condensed to a liquid with a boiling point of about -196 °C. Commonly used as a medium for long-term storage of biological materials.
litmus paperA pH indicator paper. It turns red in acidic and blue in alkaline solutions.
live recombinant vaccineA vaccine created by the expression of a pathogen antigen in a non-pathogenic organism.
live vaccineA living, non-virulent form of a pathogenic micro-organism or virus used to elicit an antibody response for the protection against infection by a virulent…
living modified organism(Abbreviation: LMO). "Living organism that possess a novel combination of genetic material obtained through the use of modern biotechnology " (Convention…
locus(LOH-kuss) Specific place where something is located or occurs. It may refer to a specific place on the body (such as an acupuncture point) or the place…
long interspersed nuclear element(Abbreviation: LINE). Families of common DNA elements, of average length 6.5 kb, which are dispersed at numerous locations within the genome.
long templateA DNA strand, synthesized during PCR, which has a primer sequence at one end but is extended beyond the site that is complementary to the second primer at…
long terminal repeat(Abbreviation: LTR). A characteristic sequence of nucleotides that occurs at each end of a retrovirus element that has become integrated into the host…
long-day plantPlants requiring a period of short nights before the switch from vegetative to reproductive growth can be initiated. See: Short-day plant.
loop bioreactorFermenters in which material is cycled between a bulk tank and a smaller tank or loop of pipes.
luteinizing hormoneA pituitary hormone which causes growth of the yellow body of the ovary and also stimulates activity of the interstitial cells of the testis.
luxury consumptionNutrient absorption by an organism in excess of that required for optimum growth and productivity.
lyaseAny of a class of enzymes that catalyse either the cleavage of a double bond and the addition of new groups to a substrate, or the formation of a double…
Lymphocyte(LIM-foh-site) A type of white blood cell. Lymphocytes have a number of roles in the immune system, including the production of antibodies and other…
lymphokineGeneric name for proteins that are released by lymphocyte s to act on other cells involved in the immune response.
lymphoma(lim-FOH-muh) Cancer that begins in cells of the immune system. There are two basic categories of lymphomas.