idiotypeAn identifying property or characteristic of an item or system. 1.A plant form expected on physiological grounds to represent an optimal type for the…
IGSAbbreviation for 1. internal guide sequence. 2. intergenic spacer.
imaginal discA mass of cells in the larvae of Drosophila melanogaster and other holometabolous insects that gives rise to particular adult organs, such as antennae…
imbibition1. The absorption of liquids or vapours into the ultramicroscopic spaces or pores found in materials. 2.
immobilized cellsCells entrapped in matrices such as alginate, polyacrylamide and agarose, for use in membrane and filter bioreactors.
immortalizationThe genetic transformation of a cell type into which can proliferate indefinitely.
Immortalizing oncogeneA gene that upon transfection enables a primary cell to grow indefinitely in culture. (See Oncogene.)
immune response(ih-MYOON reh-SPONTS) The activity of the immune system against foreign substances (antigens).
Immunity(ih-MYOO-nih-tee) The condition of being protected against an infectious disease.
immunizationA technique used to cause an immune response that results in resistance to a specific disease, especially an infectious disease.
immunoaffinity chromatographyA purification technique in which an antibody is bound to a matrix and is used to isolate a protein from a complex mixture. See: affinity chromatography.
immunoassayA test that uses the binding of antibodies to antigens to identify and measure certain substances. Immunoassays may be used to diagnose disease.
immunoglobulin(IH-myoo-noh-GLOB-yoo-lin) A type of protein that acts as an antibody.
immunoprophylaxisThe process of active or passive immunization. Active immunization with vaccines leads to long-term protection through mobilizing the organism's own…
immunosensorA biosensor having an antibody as the biological element.
immunosuppression(IH-myoo-noh-suh-PREH-shun) Suppression of the body's immune system and its ability to fight infections and other diseases.
immunosuppressorA substance, an agent or a condition that prevents or diminishes the immune response.
immunotherapy(IH-myoo-noh-THAYR-uh-pee) Treatment to boost or restore the ability of the immune system to fight cancer, infections, and other diseases.
immunotoxin(IH-myoo-noh-TOK-sin) An antibody linked to a toxic substance. Some immunotoxins can bind to cancer cells and kill them.
ImpellerAn agitator that is used for mixing the contents of a bioreactor.
in silicoIn a computer file. In the present context, the use of data bases of DNA and protein sequence to help answer biological questions.
In situ(in si'too) the natural or normal place; confined to the site of origin without invasion or spread to neighboring tissues.
in situ colonyhybridization A procedure for screening bacterial colonies or plaques growing on plates or membranes for the presence of specific DNA sequences by the…
in situ hybridizationThe visualization of in vivo location of macromolecules (particularly polynucleotides and polypeptides) by the histological staining of tissue sections or…
In vitro(in VEE-troh) In the laboratory (outside the body). The opposite of in vivo (in the body).
in vitro embryo production(Abbreviation: IVEP). The combination of ovum pickup, in vitro maturation of ova, and in vitro fertilization.
In vitro fertilization(in VEE-troh FER-tih-lih-ZAY-shun) A procedure in which eggs are removed from a woman's ovary and combined with sperm outside the body to form embryos.
in vitro maturation(Abbreviation: IVM). Culture of immature ova in the laboratory, usually until they are ready for in vitro fertilization.
in vitro transcriptionThe cell-free synthesis from DNA of RNA in the test tube. Synonym: cell-free transcription.
in vitro translationThe synthesis of proteins from isolated mRNA molecules in the test-tube. Synonym: cell-free translation.
In vivoIn the body. The opposite of in vitro (outside the body or in the laboratory).
in vivo gene therapyThe delivery of a gene or genes to a tissue or organ of a complete living individual to alleviate a genetic disorder.
in-situ conservationThe conservation of ecosystems and natural habitats and the maintenance and recovery of viable populations of species in their natural surroundings and…
inactivated agentA virus, bacterium or other organism that has been treated to prevent it from causing a disease. See: attenuated vaccine.
inbred lineThe product of inbreeding, i.e. the intercrossing of individuals that have ancestors in common.
inbreedingMatings between individuals that have one or more ancestors in common, the extreme condition being self-fertilization, which occurs naturally in many…
inbreeding depressionThe reduction in vigour over generations of inbreeding. This affects species which are normally outbreeding and highly heterozygous. See: hybrid vigour.
inclusion bodyA protein that is overproduced in a recombinant bacterium and forms a crystalline structure inside the bacterial cell.
incompatibility1. Genetically or physiologically determined prevention of intermating. 2. A physiological interaction resulting in graft rejection or failure. 3.
incompatibility groupPlasmids must belong to different incompatibility groups to co-exist within the same cell.
Incomplete dominanceA condition where a heterozygous offspring has a phenotype that is distinctly different from, and intermediate to, the parental phenotypes.
incomplete penetranceWhere the phenotype does not allow perfect prediction of the genotype as a result of interference in gene expression by the environment.
incubation1. The hatching of eggs by means of heat, either natural or artificial. 2. Period between infection and appearance of symptoms induced by a pathogen. 3.
incubatorAn apparatus in which environmental conditions (light, photoperiod, temperature, humidity, etc.
indehiscentDescribing a fruit or fruiting body that does not open to release its seeds or spores when ripe.
Independent assortmentThe random distribution during meiosis of alleles (at different genes) to the gametes that is the case when the genes in question are located on different…
indeterminate growthThe condition in which the terminal bud persists and produces successive lateral branches over an indefinite period. Opposite: determinate growth.
indirect embryogenesisPlant embryo formation on callus tissues derived from explants, including zygotic or somatic embryos and seedlings. Opposite: direct embryogenesis.
indirect organogenesisPlant organ formation on callus tissues derived from explants . Opposite: direct organogenesis.
inducerA low-molecular-weight compound or a physical agent that associates with a repressor protein to produce a complex that can no longer bind to the operator.
inducibleA gene or gene product whose transcription or synthesis is increased by exposure of the cells to an inducer or to a condition, e.g. heat.
inducible enzymeAn enzyme that is synthesized only in the presence of the substrate that acts as an inducer.
inducible geneA gene that is expressed only in the presence of a specific metabolite, the inducer.
inducible promoterThe activation of a promoter in response to either the presence of a particular compound, i.e. the inducer, or to a defined external condition, e.g.
InductionThe act or process of causing some specific effect to occur; for example the transcription of a specific gene or operon, or the production of a protein by…
induction media1. Media used to induce the formation of organs or other structures. 2. Media causing variation or mutation in the tissues exposed to it.
infiltrateThe entry of liquid into pores or other spaces.
inflorescenceThe flowers of a plant, and the way those flowers are arranged.
inheritanceThe transmission of genes and phenotypes from generation to generation.
inhibitor1. Any substance or object that retards a chemical reaction. 2. A metabolite or modifier gene that interferes with a reaction or with the expression of…
initiationCausing something to start. 1. Early steps or stages of a tissue culture process. 2. Early stages of biosynthesis.
Initiation codonThe mRNA sequence AUG, coding for methionine, which initiates translation of mRNA.
initiation factorSoluble protein required for the initiation of translation.
inoculateDeliberately introduce, in contrast to contamination. 1. In bacteriology, tissue culture, etc.
inoculation cabinetSmall room or cabinet for inoculation (of tissue or micro-organism cultures) operations, often with a current of sterile air to carry contaminants away…
inoculum(pl.: inocula) 1. A small piece of tissue cut from callus, or an explant from a tissue or organ, or a small amount of cell material from a suspension…
Inorganic compoundHistorically, chemicals that could not be derived from living processes. In modern usage, chemicals that do not contain carbon, although carbonates and a…
inositol(ih-NAH-sih-TOL) A type of sugar that has a different chemical structure than glucose (the chief source of energy for living organisms).
Inositol lipidA membrane-anchored phospholipid that transduces hormonal signals by stimulating the release of any of several chemical messengers. (See Phospholipid.)
insert1. To incorporate a DNA molecule into a cloning vector; also used as a noun to describe such a DNA molecule. 2.
insertion elementGeneric term for DNA sequences found in bacteria capable of genome insertion. Postulated to be responsible for site-specific phage and plasmid integration.
insertion mutationChanges in the base sequence of a DNA molecule resulting from the random integration of DNA from another source. See: mutation.
Insertion mutationsChanges in the base sequence of a DNA molecule resulting from the random integration of DNA from another source. See DNA, Mutation.
insertion site1. A unique restriction site in a molecule into which foreign DNA can readily be inserted.
InstabilityA lack of consistent phenotype, usually as a result of uncontrolled genetic changes.
insulin(IN-su-lin) A hormone made by the islet cells of the pancreas. Insulin controls the amount of sugar in the blood by moving it into the cells, where it can…
integrating vectorA vector that is designed to integrate cloned DNA into the host's chromosomal DNA.
IntegrationThe recombination process which inserts a small DNA molecule (usually by homologous recombination) into a larger one.
integration-excision region(Abbreviation: I/E). The portion of bacteriophage lambda (ë) DNA that enables ë-DNA to be inserted into a specific site in the E.
integumentOne of the layers that enclosed the ovule, and is the precursor of the seed coat.
intellectual property rights(Abbreviation: IPR). The legal framework, which includes patenting and plant variety protection, by which inventors control the commercial application of…