F factorAbbreviation for fertility factor. A bacterial plasmid that confers the ability to function as a genetic donor in conjugation. See: Hfr.
F1Abbreviation for filial generation 1. The initial hybrid generation resulting from a cross between two parents. See Fn.
F1, F2, FnSubsequent hybrid generations, counting from the F1. Thus, for example, F4 describes the progeny of the F3, which is the progeny of the F2 generation…
F2The second hybrid generation, produced either by intercrossing two F1 individuals, or by self-fertilizing an F1 individual. See Fn.
FABA product of hydrolysis of an IgG antibody, consisting of the variable region with some of the constant region of a heavy chain, and an entire light chain.
factorial matingA mating scheme in which each male parent is mated with each female parent. Made possible in animals by means of in vitro embryo production.
facultative anaerobeAn organism that will grow under either aerobic or anaerobic conditions.
False negativetest result that states that an analyte is absent, when, in fact, it is present above the established limit of detection for the analyte in question.
false positivetest result that states that an analyte is present, when, in fact, it is not present or, is present in an amount less than a threshold or designated…
farm animal genetic resourcesThose animal species that are used, or may be used, for the production of food and agriculture, and the populations within each of them.
farmers' privilegeRights to hold germplasm, covered by plant variety protection, as a seed source for subsequent seasons.
farmers' rightsRights first recognized by Resolution 5 of the 1989 FAO Conference as "rights arising from the past, present and future contributions of farmers in the…
FCA product of hydrolysis of an IgG antibody, consisting of parts of the constant regions of two heavy chains held together by a disulphide bridge, but…
FDAAn agency in the U.S. federal government whose mission is to protect public health by making sure that food, cosmetics, and nutritional supplements are…
fed-batch fermentationCulture of cells or micro-organisms where nutrients are added periodically to the bioreactor.
feedback inhibitionThe process by which the accumulated end product of a biochemical pathway stops synthesis of that product.
FeralRefers to an individual or population that has returned to the wild after a history of domestication.
FermentationThe anaerobic breakdown of complex organic substances, especially carbohydrates, by micro-organisms, yielding energy.
fermentation substratesMaterials used as food for growing micro-organisms. The fermentation substrates and the trace materials needed, together with chemicals added to make the…
filter bioreactorA cell culture system, in which cells are grown on a fine mesh of an inert material, which allows the culture medium to flow past it but retains the cells.
filter sterilizationProcess of removing microbial contaminants from a liquid by passing through a filter with pores too small to allow the passage of micro-organisms and…
filtration1. Separation of solids from liquids by using a porous material that only allows passage of the liquid or of solids smaller than the pore size of the…
FISHA laboratory technique used to look at genes or chromosomes in cells and tissues.
FissionThe splitting of heavier atomic nuclei into lighter ones. In the case of heavy atoms (e.g., uranium, plutonium), this will release energy.
FitnessThe survival value and the reproductive capability of an individual, compared to that of competitor individuals of the same or other species within a…
fixationThe situation in which only one allele for a given gene/locus is present in a population.
flamingA technique for sterilizing instruments, to remove live micro-organism contaminants.
Flanking regionThe DNA sequences extending on either side of a specific locus or gene.
flavin adenine dinucleotide(Abbreviation: FAD). A co-enzyme important in various biochemical reactions. It comprises a phosphorylated vitamin B2 (riboflavin) molecule linked to AMP…
flocculantA chemical agent that causes small particles to aggregate (flocculate).
flocculeA micro-organism aggregate or colloidal particle floating in or on a liquid. The cloudy appearance of micro-organism contaminated liquid media illustrates…
Flow cytometryA method of measuring the number of cells in a sample, the percentage of live cells in a sample, and certain characteristics of cells, such as size…
fluorescence immunoassay(Abbreviation: FIA). An immunoassay based on the use of fluorescence-labelled antibody.
fluorescence in situ hybridization(floor-EH-sents in SY-too HY-brih-dih-ZAY-shun) A laboratory technique used to look at genes or chromosomes in cells and tissues.
foetusPre-natal stage of a viviparous animal, between the embryonic stage and birth. AlteRNA tive spelling: fetus. See: embryo.
FogFine particles of liquid suspended in the air, such as of water in a fog chamber used for acclimatizing recent ex vitro transplants. See: mist propagation.
fold-backThe structure of a double-stranded DNA molecule formed when a molecule containing an inverted repeat sequence is denatured and then allowed to re-anneal…
folded genomeThe condensed state of the chromosomal DNA of a bacterium. The DNA is segregated into domains, and each domain is independently negatively supercoiled.
follicle stimulating hormone(Abbreviation: FSH). A hormone, secreted by the anterior pituitary gland in mammals, that stimulates the ripening of the specialized structures in the…
Food and Drug Administration (FDA)Federal agency within HHS responsible for ensuring the safety and effectiveness of drugs, biologics, vaccines, and medical devices used (among others) in…
food processing enzymeEnzyme used to control food texture, flavour, appearance, or nutritional value.
forskolinA medicinal, diterpenoid, compound exclusive to plant roots and used in the preparation of drugs for the treatment of cardiomyopathy, glaucoma and certain…
fortifyTo add strengthening components or beneficial ingredients to a nutrient medium.
forward mutationA mutation from the wild type to the mutant type. Opposite: reverse mutation.
foulingThe coating or plugging (by materials or micro-organisms) of equipment, thus preventing it from functioning properly.
founder animalAn organism that carries a transgene in its germ line and can be used in matings to establish a pure-breeding transgenic line, or one that acts as a…
founder principleThe possibility that a new, isolated population, initiated by a small number of individuals taken from a parent population, may be genetically different…
four-base cutterA type II restriction endonuclease with a four-nucleotide recognition site. Because any particular sequence of four bases occurs more frequently by chance…
fractionationDividing the total dose of radiation therapy into several smaller, equal doses delivered over a period of several days.
freeze-dryThe removal of water as vapour from frozen material under vacuum. Used to measure water content and to preserve samples, particularly spores.
fresh weightThe weight, including the water content, of a specimen. Synonym: wet weight.
FriableA term commonly used to describe a crumb-like callus. In this state, the callus is easily dissected and readily dispersed into single cells or clumps of…
functional foodA foodstuff that provides a health benefit beyond basic nutrition, demonstrating specific health or medical benefits, including the prevention and…
Functional genomicsThe field of research, that aims to determine patterns of gene expression and interaction in the genome, based on the knowledge of extensive or complete…
FungicideAn agent, such as a chemical, that kills fungi.
fungusA plant-like organism that does not make chlorophyll. Mushrooms, yeasts, and molds are examples. The plural is fungi.
Fusarium spp.A group of fungal pathogens of many economic crop species, particularly cereals, where severe infestation leads to losses in both grain yield and quality.
fusion biopharmaceuticalsFusion proteins with pharmaceutical properties. Their advantages are: 1. Synergistic activities in one molecule, i.e.
fusion gene(FYOO-zhun JEEN) A gene made by joining parts of two different genes. Fusion genes may occur naturally in the body by transfer of DNA between chromosomes.
fusion protein(FYOO-zhun PROH-teen) A protein made from a fusion gene, which is created by joining parts of two different genes.