in situ hybridization

The base pairing of a sequence of DNA to metaphase chromosomes on a microscope slide. See also chromosome, metaphase

Use of a DNA or RNA probe to detect the presence of the complementary DNA sequence in cloned bacterial or cultured eukaryotic cells.

The visualization of in vivo location of macromolecules (particularly polynucleotides and polypeptides) by the histological staining of tissue sections or cytological preparations via labelled probes/antibodies.