hormone(HOR-mone) One of many chemicals made by glands in the body. Hormones circulate in the bloodstream and control the actions of certain cells or organs.
hostIn a network, the central computer which controls the remote computers and holds the central databases.
host-specific toxinA metabolite, produced by a pathogen, and which is responsible for the adverse effects of the pathogen.
HSPOne of a group of proteins that help protect cells from stresses such as heat, cold, and low amounts of oxygen or glucose (sugar).
human artificial chromosome(Abbreviation: HAC). Analogous to yeast artificial chromosome, a construct comprising a human centromere and telomeres, which would allow for the cloning…
Human growth hormone (HGH, somatotrophin)A protein produced in the pituitary gland that stimulates the liver to produce somatomedins, which stimulate growth of bone and muscle.
hybrid dysgenesisInfertility and an increased incidence of chromosome mutations thought to be caused by the activation of transposons.
hybrid released translationA method used to identify the gene product of a cloned gene. The cloned DNA is immobilized and hybridized with a mixed mRNA sample, so that only mRNA…
hybrid seed1. Seed produced by crossing genetically dissimilar parents. 2. In plant breeding, used colloquially for seed produced by specific crosses of selected…
hybrid selectionThe process of choosing individuals possessing desired characteristics from among a hybrid population.
hybrid vigourThe extent to which a hybrid individual outperforms both its parents with respect to one or many traits.
HybridizationThe hydrogen bonding of complementary DNA and/or RNA sequences to form a duplex molecule. (See Northern hybridization, Southern hybridization.)
HybridomaA hybrid cell, composed of a B Iymphocyte fused to a tumor cell, which grows indefinitely in tissue culture and is selected for the secretion of a…
Hydrogen bondA relatively weak bond formed between a hydrogen atom (which is covalently bound to a nitrogen or oxygen atom) and a nitrogen or oxygen with an unshared…
hydrogen-uptake positive(Abbreviation: Hup+). A term describing a micro-organism that is capable of assimilating (or taking up) hydrogen gas.
HydrolysisA chemical reaction that uses water to break down a compound.
hydrophobic interactionAn interaction between a hydrophobic ('water-hating') part of a molecule and an aqueous environment.
hydroponicsThe growing of plants without soil. Plants are fed with an aerated solution of nutrients, and the roots are either supported within an inert matrix, or…
hygromycinAn antibiotic used as selective agent in bacterial and transgenic plant cell cultures.
hyperploidThe situation in which a particular chromosome or chromosome segment is present in more than the normal number. Opposite: hypoploid.
hypersensitive response1. A specific reaction of a plant to attack by a pathogen. The plant cells surrounding the point of infection rapidly die and dry out, so that pathogen…
hypersensitive siteRegions in the DNA that are highly susceptible to digestion with restriction endonucleases.
hypertonicA solution with an osmotic potential greater than that of living cells. Treatment with such solutions leads to the plasmolysis of cells.
hypervariable regionThe parts of both the heavy and light chains of an antibody molecule that enable it to bind to a specific site on an antigen.
hypervariable segmentA region of a protein that varies considerably between strains or individuals.
hypocotylThe portion of an embryo or seedling below the cotyledons . A transitional area between stem and root.
hypomorphA mutation that reduces, but does not completely abolish gene expression.
hypoplasticDefective and reduced growth or development (e.g. dwarfing and stunting in plants) resulting from an abnormal condition, for example disease or…
hypoploidThe situation in which a particular chromosome or chromosome segment is present in less than the normal number. Opposite: hyperploid.
hypothalamic peptidesPeptides generated in the vertebrate forebrain and concerned with regulating the body's physiological state.
hypotonicOsmotic potential less than that of living cells. Cells placed in a hypotonic solution will absorb water and display swelling and turgidity.