LacunaeThe spaces occupied by cells (e.g., chondrocytes and osteocytes) of calcified tissues.
LeftyA developmental factor that helps determine right-left asymmetry in vertebrates.
LeptinA hormone produced by the placenta and fetal tissues that acts as a growth factor and modulator of metabolic and immune functions.
Leukemia inhibitory factorA cell messenger protein originally noted for inhibition of mouse M1 myeloid leukemia cells that also has effects including inhibiting differentiation to…
Leukemia inhibitory factor (LIF)A growth factor necessary for maintaining mouse embryonic stem cells in a proliferative, undifferentiated state.
Leukocyte(LOO-koh-site) A white blood cell. Refers to a blood cell that does not contain hemoglobin.
Leukocyte (White Blood Cell)The general name for a white blood cell. Leukocytes are responsible for maintaining the immune system's response to foreign substances and infection.
Leukocyte common antigenCell-surface molecule found on white blood cells and white blood cell progenitors. Also referred to as CD45.
LineageA chart that traces the flow of genetic information from generation to generation.
Lineage surface antigen (Lin)A mixture of monoclonal antibodies that are directed against antigens found on mature hematopoietic cells of different lineages.
LipaseA class of enzymes which break down lipids into their component fatty acids and glycerol.
Long-term self-renewalThe ability of stem cells to renew themselves by dividing into the same non-specialized cell type over long periods (many months to years) depending on…
Lymph NodeA small rounded or bean-shaped mass of lymphatic tissue that helps the body's immune system.
Lymph nodes(LIMF nohdz): Small glands that help the body fight infection and disease. They filter a fluid called lymph and contain white blood cells.
Lymphatic system(lim-FA-tik SIS-tem) The tissues and organs that produce, store, and carry white blood cells that fight infections and other diseases.
Lymphocyte(LIM-foh-site) A type of white blood cell. Lymphocytes have a number of roles in the immune system, including the production of antibodies and other…
Lymphoid(LIM-foyd) Referring to lymphocytes, a type of white blood cell. Also refers to tissue in which lymphocytes develop.