Dideoxynucleotide (didN)

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Food Biotechnology

A deoxynucleotide that lacks a 3' hydroxyl group, and is thus unable to form a 3'-5' phosphodiester bond necessary for chain elongation. Dideoxynucleotides are used in DNA sequencing and the treatment of viral diseases. (See Nucleotide.)

Susan Allender-Hagedorn and Charles Hagedorn — An Agricultural and Environmental Biotechnology Annotated Dictionary