Exonuclease
Science› Biotechnology and Genetics
Food Biotechnology
An enzyme that digests DNA or RNA, beginning at the end of a strand. It therefore requires a free end in order to begin the degradation. 5'-exonucleases require a free 5' end and degrade the molecule in the 5'?3' direction. 3'-exonucleases require a free 3' end and degrade in the opposite direction.
Science› Biotechnology and Genetics
Human Genome
An enzyme that cleaves nucleotides sequentially from free ends of a linear nucleic acid substrate.