Reading frame

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Food Biotechnology

A series of triplet codons beginning from a specific nucleotide. Depending on where one begins, each DNA strand contains three different reading frames. (See Open reading frame, Overlapping reading frames.)

Susan Allender-Hagedorn and Charles Hagedorn — An Agricultural and Environmental Biotechnology Annotated Dictionary

The reading frame defines which sets of three nucleotides are read as triplets, and hence as codons, in DNA transcription. The start point is usually determined by the initiation codon, AUG. Thus the sequence AUGGCAAAA would be read as AUG/GCA/AAA not as A/UGC/CAA/AA. See: open reading frame.

UN Food and Agriculture Organization — Glossary of Biotechnology for Food and Agriculture