DormancyA period in which a plant does not grow, awaiting necessary environmental conditions such as temperature, moisture, nutrient availability.
dosage compensationA regulatory mechanism for sex-linked genes, to allow equivalent levels of gene expression from (in mammals) XY or XX genotypes, even though the gene copy…
double crossing-overThe formation of two chiasmata within a chromosome arm, leading to the generation of a double recombinant gamete with respect to genes located within the…
double fertilizationA process, unique to flowering plants, in which two male nuclei, which have travelled down the pollen tube, separately fuse with different female nuclei…
Double helixDescribes the coiling of the antiparallel strands of the DNA molecule, resembling a spiral staircase in which the paired bases form the steps and the…
double recessiveAn organism homozygous for a recessive allele at each of two loci.
double-stranded DNA(Abbreviation: dsDNA ). Two complementary strands of DNA annealed in the form of a double helix. Synonym: duplex DNA.
doubling time(DUH-bling...) In biology, the amount of time it takes for one cell to divide or for a group of cells (such as a tumor) to double in size.
down promoter mutationA mutation that decreases the frequency of initiation of transcription. This leads to a fall in the level of mRNA compared to the wild type state.
down-regulateTo induce genetically a reduction in the level of a gene's expression.
downstreamThe region extending in a 3' direction from a gene.
downstream processingA general term for biotechnological processes which follow the biology, i.e. fermentation of a micro-organism or growth of a plant.
Drosophila melanogasterThe fruit fly, used for many years as a model for eukaryotic genetics. Of the nearly 300 disease-causing genes in the human genome, more than half have an…
drugAny substance, other than food, that is used to prevent, diagnose, treat or relieve symptoms of a disease or abnormal condition.
drug deliveryMethod by which a drug is delivered to its site of action. For traditional drugs this is another name for formulation.
dry weightThe weight of tissue obtained following sufficiently prolonged oven-drying at high temperature to remove all water.
dTTPRarely used but strictly correct abbreviation for deoxythymidine 5'-triphosphate. Required for DNA synthesis since it is a direct precursor molecule.
dual cultureA culture made of a plant tissue and one organism (such as a nematode) or an obligate parasite/micro-organism (such as a fungus).
EBVA common virus that remains dormant in most people. It causes infectious mononucleosis and has been associated with certain cancers, including Burkitt…
elastinA fibrous protein that is the major constituent of the yellow elastic fibres of animal connective tissue.
electro-blottingThe electrophoretic transfer of DNA, RNA or protein from a gel, in which they have been separated, to a support matrix, such as nitrocellulose.
electrochemical sensorBiosensors, such as an enzyme electrode, in which a biological process is harnessed to an electrical sensor system.
electron microscope(ee-LEK-tron MY-kroh-SKOPE) A microscope (device used to magnify small objects) that uses electrons (instead of light) to produce an enlarged image.
Electrophoresisa technique for the separation of charged molecules by migration on a support medium under the influence of an electrical charge.
ElectroporationA method for transforrning DNA, especially useful for plant cells, in which high voltage pulses of electricity are used to open pores in cell membranes…
ELISAAbbreviation for enzyme-linked immunosorbent assay. An immunoassay, i.e. an antibody -based technique for the diagnosis of the presence and quantity of…
elite treeA phenotypically superior tree in a tree breeding programme.
elongation factorsSoluble proteins required for the elongation of polypeptide chains on ribosomes.
EmbryoEarly stage in the development of a plant or an animal. In vertebrate animals (have a backbone or spinal column), this stage lasts from shortly after…
embryo cloningThe creation of identical copies of an embryo by embryo splitting or by nuclear transfer from undifferentiated embryonic cells.
embryo multiplication and transfer(Abbreviation: EMT). The cloning of animal embryos and their subsequent transfer to recipients via artificial inembryonation.
embryo rescueA sequence of tissue culture techniques utilized to enable a fertilized immature embryo resulting from an interspecific cross to continue growth and…
embryo sacThe mature female gametophyte in angiosperms. Generally a seven-celled structure - two synergids, one egg cell, three antipodal cells (each with a single…
embryo sexingThe determination of the sex of an embryo prior to birth. Typically achieved by the polymerase chain reaction -mediated amplification of DNA extracted…
embryo splittingThe splitting of young embryos into several sections, each of which develops into an animal. A form of animal cloning, i.e.
embryo storageCryogenic preservation of animal embryos, allowing inembryonation or other manipulations long after embryo formation.
embryo technologyGeneric name for any modification of mammalian embryos. It encompasses embryo cloning, embryo splitting, embryo storage, and in vitro fertilization.
embryo transfer(Abbreviation: ET). See: embryo multiplication and transfer, multiple ovulation and embryo transfer.
embryogenesis1. (General) Development of an embryo. 2. (In plants) In vitro formation of plants from plant tissues, through a pathway closely resembling normal…
embryoidPlant biotechnology term no longer commonly used. An embryo-like body developing in vitro, forming a complete, self-contained plantlet with no vascular…
Embryonic stem (ES) cellsCell lines derived from early embryos that have the potential to differentiate into all types of somatic cells as well as to form germ line cells, and…
Embryonic stem cells(Abbreviation: ES cells). Cells of the early embryo that can give rise to all differentiated cells, including germ line cells.
emission wavelengthThe specific wavelength of light emitted by a fluorescent molecule, such as a labelled probe, upon absorption of light at the (higher) excitation…
EncapsidationProcess by which a virus' nucleic acid is enclosed in a capsid. See Coat protein.
encapsulating agentsAnything which forms a shell around an enzyme or bacterium, common agents being polysaccharides such as alginate or agar.
encapsulationAny method packaging an enzyme or bacterium and maintaining its normal functions. Used to immobilize cells in a bioreactor.
encodeThe gene product specified by a particular nucleic acid sequence. See: genetic code.
end-labellingThe introduction of a readily-visualized tag at the end of a DNA or RNA molecule.
end-product inhibitionThe inhibition of an enzyme by a metabolite. Typically, the enzyme is the first enzyme in a biosynthetic pathway, and the metabolite the product of the…
Endangered speciesA plant or animal species in immediate danger of extinction because its population number has reached a critical level, or its habitat has been…
EndemicWhere disease occurs on a consistent basis.
endocrine glandAny gland in an animal that manufactures hormones and secretes them directly into the bloodstream to act at distant sites in the body, known as target…
endocytosisThe process by which materials enter a cell without passing through the cell membrane.
EndodermThe internal layer of cells of the gastrula, which develops into the alimentary canal (gut) and digestive glands of the adult.
endodermisThe layer of living cells, with various characteristically thickened walls and no intercellular spaces, which surrounds the of certain plants and occurs…
endoplasmic reticulum(Abbreviation: ER). A cytoplasmic net of membranes, adjacent to the nucleus, visible under the electron microscope. The sites of protein synthesis.
endopolyploidyThe net result of endomitoses. The somatic chromosome number has doubled (or more), forming a polyploid cell line.
endoproteaseAn enzyme that cleaves internal peptide bonds within a polypeptide molecule. Site of cleavage is usually specific to certain amino acid residues.
endoreduplicationChromosome reproduction during interphase. Four-chromatid chromosomes (diplochromosomes) are seen during this phase.
endospermThe nutritive tissue that develops in the seed of most angiosperms, containing varying proportions of carbohydrate (usually starch), protein and lipid.
endosperm mother cellOne of the seven cells of the mature plant embryo sac, containing the two polar nuclei and, which, following fertilization, gives rise to the primary…
endotoxinA component of the cell wall of gram-negative bacteria that elicits, in mammals, an inflammatory response and fever.