antiparallel orientation

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Food Biotechnology

The normal arrangement of the two strands of a double-stranded DNA molecule, and of other nucleic-acid duplexes (DNA -RNA, RNA -RNA ), in which the two strands are oriented in opposite directions so that the 5'-phosphate end of one strand is aligned with the 3'-hydroxyl end of the complementary strand.

UN Food and Agriculture Organization — Glossary of Biotechnology for Food and Agriculture