Z-DNA

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Science› Biotechnology and Genetics

Food Biotechnology

A region of DNA that is "flipped" into a lefthanded helix, characterized by alternating purines and pyrimidines, and which may be the target of a DNA-binding protein.

A form of DNA, in which the double helix is wound in a left-hand, instead of a right-hand, manner. DNA adopts the Z conformation when purines and pyrimidines alternate on each strand, e.g. 5'CGCGCGCG 3' or 3'GCGCGCGC5'. Synonym: zig-zag DNA.

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