covalently-closed circular DNA

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Food Biotechnology

(Abbreviation: ccc DNA). A DNA molecule in which the free ends have ligated to form a circle. The strands remain linked together even after denaturation. Plasmids exist in this form in their in vivo state. In its native form, ccc DNA will adopt a supercoiled configuration. See: circularization.

UN Food and Agriculture Organization — Glossary of Biotechnology for Food and Agriculture