T4 DNA ligase

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Food Biotechnology

An enzyme, present in bacteria infected with bacteriophage T4, which catalyses the joining (ligation ) of, and repairs nicks in, duplex DNA molecules. Ligation activity requires that one DNA molecule has a 5'-phosphate group, and that the other has a free 3'-hydroxyl group.

UN Food and Agriculture Organization — Glossary of Biotechnology for Food and Agriculture