Gene amplification

The presence of multiple genes. Amplification is one mechanism through which proto-oncogenes are activated in malignant cells.

The selective production of multiple copies of one gene without a proportional increase in others.

An increase in the number of copies of any particular piece of DNA. A tumor cell amplifies, or copies, DNA segments naturally as a result of cell signals and sometimes environmental events. See also cell, gene, oncogene

Repeated copying of a piece of DNA; a characteristic of tumor cells. See also: gene, oncogene