oncogene

A gene that contributes to cancer formation when mutated or inappropriately expressed. (See Cellular oncogene, Dominant oncogene, Immortalizing oncogene, Recessive oncogene.)

A gene that causes cells to grow in an uncontrolled (i.e. tumourous) manner. Oncogenes are mutant forms of normal functional genes (called proto-oncogenes) that have a role in regulating cell proliferation. See: cellular oncogene; ; immortalizing oncogene; recessive oncogene, p53 gene.

A gene that normally directs cell growth. If altered, an oncogene can promote or allow the uncontrolled growth of cancer. Alterations can be inherited or caused by an environmental exposure to carcinogens.

A gene that is capable of causing the transformation of normal cells into cancer cells. See also cancer, gene, protein

A gene, one or more forms of which is associated with cancer. Many oncogenes are involved, directly or indirectly, in controlling the rate of cell growth.