Transition-state intermediate

In a chemical reaction, an unstable and high-energy configuration assumed by reactants on the way to making products. Enzymes are thought to bind and stabilize the transition state, thus lowering the energy of activation needed to drive the reaction to completion.

In a chemical reaction, an unstable and high-energy configuration assumed by reactants on the way to making products. Enzyme s are thought to bind and stabilize the transition state, thus lowering the energy of activation needed to drive the reaction to completion.