DNAse

Abbreviation for deoxyribonuclease. Any enzyme that catalyses the cleavage of DNA phosphodiester bond s. DNAse I is a digestive endonuclease secreted by the pancreas, that degrades DNA into shorter fragments. Many other endonucleases and exonucleases are involved in DNA repair and replication. Synonym: DNAase. See: restriction endonuclease.