megaDalton(Abbreviation: MDa). One megaDalton is equal to 106 Dalton.
megagametophyteThe female gametophyte; the plant that develops from a megaspore.
megasporeThe female gametophyte in heterosporous plants. Synonym: macrospore.
MeiosisA special form of cell division in which each daughter cell receives half the amount of DNA as the parent cell.
meiotic analysisThe use of patterns of chromosome pairing at meiotic prophase and metaphase to detect relationships between chromosomes, from which can be deduced the…
meiotic driveAny mechanism that causes a particular allele or chromosome to be over-represented in a population of gametes.
melanin(MEH-luh-nin) A pigment that gives color to skin and eyes and helps protect it from damage by ultraviolet light.
melting temperature(Abbreviation: Tm). The temperature at which a double-stranded DNA molecule denatures into separate single strands.
membrane bioreactorA vessel in which cells are cultured on or behind a permeable membrane, which allows the diffusion of nutrients to the cells, but retains the cells…
memory cellLong-lived B cells and T cells that mediate rapid secondary immune responses to a previously encountered antigen.
Mendel's LawsTwo laws summarizing Gregor Mendel's theory of inheritance. The Law of Segregation states that each hereditary characteristic is controlled by two…
Mendelian populationA natural, interbreeding unit of sexually reproducing plants or animals sharing a common gene pool.
mericlinalRefers to a chimera with tissue of one genotype partly surrounded by that of another genotype.
mericloningA propagation method using shoot tips in culture to proliferate multiple buds, which can then be separated, rooted and planted out.
meristeleThe branch of a stele supplying the leaf.
meristemUndifferentiated but determined plant tissue, in which the cells are capable of active division and differentiation into specialized tissues such as…
meristem cultureA tissue culture containing meristematic dome tissue without adjacent leaf primordia or stem tissue.
meristem tipAn explant comprising the meristem (meristematic dome) and usually one pair of leaf primordia.
meristem tip cultureCultures derived from meristem tip explants . Used widely to achieve virus elimination and axillary shoot proliferation, less commonly for callus…
meristemoidA localized group of callus cells, characterized by their accumulation of starch, RNA and protein, and giving rise to adventitious shoots or roots.
merozygotePartial zygote produced by a process of partial genetic exchange, such as transformation in bacteria.
Messenger RNA (mRNA)The class of RNA molecules that copies the genetic information from DNA, in the nucleus, and carries it to ribosomes, in the cytoplasm, where it is…
metabolic cellA cell that is not dividing. See: metabolism
metabolism(meh-TA-boh-lih-zum) The total of all chemical changes that take place in a cell or an organism.
metabolite(meh-TA-boh-lite) A substance made or used when the body breaks down food, drugs or chemicals, or its own tissue (for example, fat or muscle tissue).
metabolomicsThe large-scale study of the full complement of secondary metabolites produced by a given species in all its tissues and growth stages.
metacentric chromosomeA chromosome in which the centromere is located in the middle and, consequently, the chromosome arms are of about equal length.
metal affinity chromatographyA chromatographic technique, in which a compound interacting with a specific metal ion can be captured by immobilizing the relevant ion on the column's…
metalloenzymeAn enzyme which requires the presence of a metal in order to be catalytically active.
MetallothioneinA protective protein that binds heavy metals, such as cadmium and lead.
MetaphaseStage of mitosis or meiosis (following prophase and preceding anaphase ) during which the chromosome s, or at least the kinetochores, lie in the central…
metastasis(meh-TAS-tuh-sis) The spread of cancer from one part of the body to another. A tumor formed by cells that have spread is called a "metastatic tumor" or a…
methylationThe addition of a methyl group (-CH3) to a molecule, most commonly in the context of DNA where cytosine and, less often, adenine residues can be modified…
MHCAbbreviation for major histocompatibility complex.
micro-arrayA large set of cloned DNA molecules immobilized as a compact and orderly pattern of sub-microlitre spots onto a solid matrix (typically a glass slide).
micro-carrierSmall particles used as a support material for (particularly mammalian) cells, which are too fragile to be pumped and stirred as bacterial cells are in a…
micro-elementA nutritional element required in very small quantities.
micro-encapsulationA process of enclosing a substance in very small sealed capsules from which material is released by heat, solution or other means.
micro-environmentA small-scale environment in which the conditions (temperature, humidity, pH etc.
micro-injectionThe introduction of small amounts of (usually) liquid material (DNA, RNA, enzyme s, cytotoxic agents) into a defined tissue or single cell with a fine…
micro-isolating systemMechanical separation of single cells or protoplasts thus allowing them to proliferate individually.
micro-organismOrganism visible only under magnification.
microalgal cultureCulture in bioreactors of microalgae (including seaweeds).
microbodyA frequently spherical cellular organelle, bound by a single membrane, 20-60 nm in diameter, and containing a variety of enzymes.
microdroplet array(Abbreviation: MDA). A technique used to simultaneously evaluate large numbers of media modifications, employing small quantities of medium into which are…
microfibrilMicroscopic fibres visible only at the high magnification of the electron microscope.
micropropagationMiniaturized in vitro multiplication and/or regeneration of plant material under aseptic and controlled environmental conditions.
micropyle1. A small opening in the surface of a plant ovule through which the pollen tube passes prior to fertilization. 2.
microsatelliteA short sequence of DNA, usually 1 to 4 basepairs (a unit of DNA), that is repeated together in a row along the DNA molecule.
microsporeThe immature male gametophyte in seed plants; the haploid male cell that ripens into a pollen grain.
microtuberMiniature tuber, produced in tissue culture, which is readily regenerable into a normal tuberous plant.
MicrotubuleSelf-assembling components of the cytoskeleton. Microtubules are cylindrical protein polymers, interconnected by cross-bridging proteins, which…
mid-parent valueThe average of the phenotypic measure, with respect to a given trait, of the two parents used to generate the population being analysed.
middle lamellaA thin exclusively plant membrane separating two adjacent protoplasts and remaining as a distinct cementing layer between adjacent cell walls.
mineralizationThe conversion of organic compounds into inorganic (mineral) ones. For example, the conversion of ethanol into carbon dioxide and water.
mini-prepA small-scale preparation of plasmid or phage DNA. Used to purify cloned DNA from the DNA of the vector.
Minimal tillage practicesPractices that allow farmers to reduce the tilling of the land to conserve topsoil and its nutrients.
minimum effective cell densityThe cell density below which reproducible cell growth fails. The minimum density is determined by both the source function of the tissue (species…
minimum inoculum sizeThe critical volume of inoculum required to initiate culture growth, due to the diffusive loss of cell materials into the medium.
minisatelliteA form of variable number tandem repeats in which the repeat unit size ranges from 10-100 bp. Used for DNA fingerprinting following Southern hybridization.
minituberSmall tubers (5-15 mm in diameter) formed on shoot cultures or cuttings of tuber-forming crops, such as potato.
mismatchThe occurrence of a non-complementary pairs of bases in a double helix of DNA, e.g. A:C, G:T.
mismatch repairA DNA repair process that corrects mismatched base pairs.
missense mutationA mutation that changes a codon for one amino acid into a codon specifying another amino acid.
mist propagationApplication of fine droplets of water to maintain humidity around plantlets or cuttings, which have not yet developed effective roots.
miteFree-living and parasitic arachnids. Infestation of plant crops reduces yield through the destruction of leaf tissue.
Mitochondrial DNA(Abbreviation: mtDNA). A circular DNA found in mitochondria. In mammals, mtDNA makes up less than 1% of the total DNA, but in plants the amount is…
mitochondrion(pl.: mitochondria) Organelle possessing its own DNA which appear in all eukaryotic cells (and never in prokaryotic cells) and produce adenosine…
mitogenA substance that can cause cells to initiate mitosis.
Mitosis(my-TOH-sis) The process by which a single parent cell divides to make two new daughter cells.
mixed budA bud containing both rudimentary leaves and flowers.
mixoploidGroups of cells with variable (a mix of euploid, aneuploid, polyploid ) chromosome numbers.
mobilization1. The transfer between bacteria of a non-conjugative plasmid by a conjugative plasmid. 2.
mobilizing functionThe genes on a plasmid that give it the ability to facilitate the transfer of either a non-conjugative or a conjugative plasmid from one bacterium to…
modeIn a frequency distribution, the class having the greatest frequency.
modern biotechnologyThe application of: a. In vitro nucleic acid techniques, including recombinant deoxyribonucleic acid (DNA ) and direct injection of nucleic acid into…
ModificationAny change to the terms of a mortgage loan, including changes to the interest rate, loan balance, or loan term.
modifying geneA gene that affects the expression of some other gene.
MOETAbbreviation for multiple ovulation and embryo transfer.
Molecular biologyThe study of the biochemical and mo- lecular interactions within living cells.